Iron-catalyzed Glycal cis-Aminoacyloxylation for 2-amino saccharide synthesis

IF 1.5 4区化学 Q3 CHEMISTRY, ORGANIC

Tetrahedron Letters Pub Date : 2025-05-28 DOI:10.1016/j.tetlet.2025.155678

Le Yin , Dakang Zhang , Zixiang Jiang, Pinzhi Wang, Joseph C. Levine, Dylan L. Labbe, Hao Xu

引用次数: 0

Abstract

We report here a new catalytic and exclusively 1,2-cis-selective glycal aminoacyloxylation method for 2-amino saccharide synthesis. This iron-catalyzed glycosylation is effective for a wide variety of glycosyl donors with consistently high stereoselectivity and excellent functional-group compatibility, which facilitates late-stage amino group incorporation for complex-carbohydrate synthesis.

Abstract Image

查看原文本刊更多论文

铁催化糖基顺式氨基酰基化合成2-氨基糖

我们报道了一种新的催化和完全1,2-顺式选择性糖基氨基酰化合成2-氨基糖的方法。这种铁催化的糖基化对各种糖基供体都有效，具有一贯的高立体选择性和良好的官能团相容性，有助于后期氨基结合以合成复杂的碳水化合物。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

求助全文

约1分钟内获得全文求助全文

来源期刊

Tetrahedron Letters 化学-有机化学

CiteScore

3.50

自引率

5.60%

发文量

521

审稿时长

28 days

期刊介绍： Tetrahedron Letters provides maximum dissemination of outstanding developments in organic chemistry. The journal is published weekly and covers developments in techniques, structures, methods and conclusions in experimental and theoretical organic chemistry. Rapid publication of timely and significant research results enables researchers from all over the world to transmit quickly their new contributions to large, international audiences.