Photodynamic therapy in ocular oncology: A bibliometric analysis (1987–2024)

IF 3.1 3区医学 Q2 ONCOLOGY

Photodiagnosis and Photodynamic Therapy Pub Date : 2025-05-28 DOI:10.1016/j.pdpdt.2025.104654

Ceren Türkoğlu , Aslan Aykut

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引用次数: 0

Abstract

Background

Photodynamic therapy (PDT) is a minimally invasive modality widely employed in ocular oncology, utilizing photosensitizers such as verteporfin to induce localized cytotoxic effects. While PDT is commonly applied in the management of benign intraocular tumors and selectively for malignant lesions, bibliometric analyses in this field remain scarce. This study aims to address this gap by analyzing bibliometric trends and mapping the evolution of PDT research in ocular oncology.

Methods

A bibliometric analysis was conducted using the Web of Science Core Collection, targeting PDT in ocular tumors. Data were screened for relevance, refined using OpenRefine, and analyzed in Microsoft Excel for publication trends. VOSviewer was used to visualize collaboration networks and keyword co-occurrence. Key indicators such as publication output, citations, authorship, institutional contributions, and journal distribution were assessed.

Results

A total of 177 publications (1987–2024) were identified, with original articles comprising 67.7 %. The United States led in publication count (n = 63), total citations (1074), and H-index (20). Investigative Ophthalmology & Visual Science and Retina were the most prolific journals. A decline in publication volume was noted post-2020, coinciding with a global verteporfin shortage. Keyword analysis showed a primary focus on circumscribed choroidal hemangioma, with recent interest shifting toward metastasis and alternative therapies. The most prolific authors were Shields CL and Shields JA, while Schmidt-Erfurth U had the highest citation count.

Conclusion

This study presents a comprehensive bibliometric mapping of PDT in ocular oncology, highlighting research trends, influential contributors, and the impact of external factors on scholarly output.

查看原文本刊更多论文

眼肿瘤的光动力疗法：文献计量学分析（1987-2024）。

背景：光动力治疗（PDT）是一种广泛应用于眼部肿瘤的微创治疗方式，利用光敏剂如维替泊芬来诱导局部细胞毒性作用。虽然PDT通常用于良性眼内肿瘤的治疗，并选择性地用于恶性病变，但这一领域的文献计量分析仍然很少。本研究旨在通过分析文献计量学趋势和绘制眼部肿瘤中PDT研究的演变来解决这一差距。方法：使用Web of Science Core Collection进行文献计量学分析，以眼部肿瘤中的PDT为目标。对数据进行相关性筛选，使用OpenRefine进行精炼，并在Microsoft Excel中分析出版趋势。使用VOSviewer可视化协作网络和关键词共现。评估了诸如出版物产出、引用、作者、机构贡献和期刊分布等关键指标。结果：共检索到177篇文献（1987-2024），其中原创文献占67.7%。美国在发表数（n=63）、总引用数（1074）和h指数（20）方面领先。《调查眼科学与视觉科学》和《视网膜》是最多产的期刊。报告指出，2020年后出版物数量下降，恰逢全球维替泊芬短缺。关键词分析显示，主要关注局限脉络膜血管瘤，最近的兴趣转移到转移和替代治疗。最多产的作者是Shields CL和Shields JA，而Schmidt-Erfurth U的引用数最高。结论：本研究首次对眼部肿瘤学的PDT进行了全面的文献计量测绘，突出了研究趋势、有影响力的贡献者以及外部因素对学术产出的影响。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Photodiagnosis and Photodynamic Therapy ONCOLOGY-

CiteScore

5.80

自引率

24.20%

发文量

509

审稿时长

50 days

期刊介绍： Photodiagnosis and Photodynamic Therapy is an international journal for the dissemination of scientific knowledge and clinical developments of Photodiagnosis and Photodynamic Therapy in all medical specialties. The journal publishes original articles, review articles, case presentations, "how-to-do-it" articles, Letters to the Editor, short communications and relevant images with short descriptions. All submitted material is subject to a strict peer-review process.