Acute annular outer retinopathy: initial insights into clinical course variations with multimodal imaging.

IF 2.8 4区 医学 Q1 OPHTHALMOLOGY
Chunli Chen, Yizhe Cheng, Haiying Zhou, Yongpeng Zhang, Xiaoyan Peng
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引用次数: 0

Abstract

Objective: To describe the clinical course and provide initial imaging perspectives in acute annular outer retinopathy (AAOR) by reviewing multimodal imaging (MMI) findings.

Design: Observational case series study.

Participants: Nine patients (12 eyes) with AAOR.

Methods: Review clinical charts and MMI findings.

Main outcome measures: Clinical medical records and multimodal imaging features via fundus photographs, optical coherence tomography (OCT), fundus autofluorescence (AF) and OCT angiography (OCTA), as applicable.

Results: Twelve eyes of nine patients (18-39 years) were identified. The clinical course was subdivided acutely progressive stage (APS), stationary stage (SS) and atrophic stage (AS) (1-3 weeks, 3 weeks to 3 months and >3 months, respectively). During APS, advancement of peripapillary annular band was noted in all eyes, accompanied by absent ellipsoid zone, increased choroidal thickness (ChT) and thinned outer nuclear layer (ONL) within the affected area. During SS, annular band disappeared on fundus photograph with improved ONL with improved ONL. During AS, affected area became depigmented with scattered pigmentation, exhibiting hyper-AF or mixed AF. Other manifestations included retinal atrophy and decreased ChT. OCTA revealed an enlarged foveal avascular zone in each stage, especially in AS. Seven eyes of 5 patients showed no macular involvement with best corrected visual acuity (BCVA) of 20/20, while 5 eyes of 5 patients showed macular involvement with poorer BCVA of HM-20/400 at the last visit.

Conclusions: AAOR mostly occurs in young individuals with unilateral involvement, especially in those with mild to moderate myopia. The observed variations in the clinical course of AAOR, documented through MMI, aid in the prompt recognition and understanding of this rare entity.

急性环形外视网膜病变:临床过程变化与多模态成像的初步见解。
目的:通过回顾多模态影像学(MMI)的发现,描述急性环形外视网膜病变(AAOR)的临床过程并提供初步影像学视角。设计:观察性病例系列研究。受试者:AAOR患者9例(12眼)。方法:回顾临床图表和MMI的表现。主要结果测量:临床医疗记录和眼底照片、光学相干断层扫描(OCT)、眼底自体荧光(AF)和OCT血管造影(OCTA)等多模态成像特征(如适用)。结果:9例患者(18 ~ 39岁)12只眼。临床病程分为急性进展期(APS)、静止期(SS)和萎缩期(AS),分别为1 ~ 3周、3周~ 3个月和10 ~ 3个月。APS期间,所有眼均可见乳头周围环状带推进,伴椭球区缺失,脉络膜厚度(ChT)增加,受累区域内外核层(ONL)变薄。在SS期间,改进的ONL图像中环状带消失。AS期间,受累区域色素脱色,色散,表现为高度AF或混合性AF,其他表现为视网膜萎缩,ChT减少。OCTA显示各期中央凹无血管区增大,尤其是AS。5例患者7眼无黄斑受累,最佳矫正视力(BCVA)为20/20,5例患者5眼有黄斑受累,BCVA较差,为HM-20/400。结论:AAOR多发生在单侧受累的青少年,尤其是轻中度近视患者。通过MMI记录的AAOR临床过程中观察到的变化有助于及时识别和理解这种罕见的实体。
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来源期刊
CiteScore
3.20
自引率
4.80%
发文量
223
审稿时长
38 days
期刊介绍: Official journal of the Canadian Ophthalmological Society. The Canadian Journal of Ophthalmology (CJO) is the official journal of the Canadian Ophthalmological Society and is committed to timely publication of original, peer-reviewed ophthalmology and vision science articles.
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