V V Udut, V P Demkin, S V Melnichuk, T V Rudenko, M V Svetlik, M D Akinina, O V Demkin, L V Smaglii, V M Alifirova, O V Grebenuk
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引用次数: 0
Abstract
A numerical experiment was conducted to determine the spectral sensitivity and selectivity of the cellular components of the utricle and saccule of a laboratory animal (rat) to a periodic electrical stimulation. Equivalent electrical circuit of otolith replacement was used. Its parameters were determined from the anatomical structure and from the measured specific characteristics of cellular elements taking into account the changing ionic conductivity. It was found that the frequency dependence of the impedance and the spectral sensitivity of the cell elements for the utricle and saccule have a resonant nature. The obtained data about the mechanisms of electrical stimulation of hair cells, their spectral sensitivity, and frequency selectivity can serve as the basis for choosing the optimal mode of electrical stimulation in a vestibular implant.
期刊介绍：
Bulletin of Experimental Biology and Medicine presents original peer reviewed research papers and brief reports on priority new research results in physiology, biochemistry, biophysics, pharmacology, immunology, microbiology, genetics, oncology, etc. Novel trends in science are covered in new sections of the journal - Biogerontology and Human Ecology - that first appeared in 2005.
World scientific interest in stem cells prompted inclusion into Bulletin of Experimental Biology and Medicine a quarterly scientific journal Cell Technologies in Biology and Medicine (a new Russian Academy of Medical Sciences publication since 2005). It publishes only original papers from the leading research institutions on molecular biology of stem and progenitor cells, stem cell as the basis of gene therapy, molecular language of cell-to-cell communication, cytokines, chemokines, growth and other factors, pilot projects on clinical use of stem and progenitor cells.
The Russian Volume Year is published in English from April.
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