Studies toward the synthesis of strasseriolide A & B via a ring-closing metathesis strategy

IF 1.5 4区化学 Q3 CHEMISTRY, ORGANIC

Tetrahedron Letters Pub Date : 2025-05-29 DOI:10.1016/j.tetlet.2025.155669

Bashweshawar S. Dhulshette , Shikha Mittal , Subhash Ghosh

引用次数: 0

Abstract

This communication describes a synthetic approach for strasseriolide A & B via ring-closing metathesis reaction. The stereoselective synthesis of key olefin fragments, followed by their assembly, yielded the crucial bis-olefinic intermediate. However, despite our best efforts, the critical ring-closing metathesis reaction was unsuccessful.

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闭环复合策略合成strasseriolide A和B的研究

本通讯描述了一种合成strasseriolide a的方法；B通过闭合环复合反应。关键烯烃片段的立体选择性合成及其组装，产生了关键的二烯烃中间体。然而，尽管我们尽了最大的努力，关键的合环复合反应还是没有成功。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Tetrahedron Letters 化学-有机化学

CiteScore

3.50

自引率

5.60%

发文量

521

审稿时长

28 days

期刊介绍： Tetrahedron Letters provides maximum dissemination of outstanding developments in organic chemistry. The journal is published weekly and covers developments in techniques, structures, methods and conclusions in experimental and theoretical organic chemistry. Rapid publication of timely and significant research results enables researchers from all over the world to transmit quickly their new contributions to large, international audiences.