Childhood vaccination catch-up and recovery plans for mitigating immunity gap post the COVID-19 pandemic: A case study of selected African countries

IF 4.5 3区 医学 Q2 IMMUNOLOGY
Abu Sadat Mohammad Sayem, Godfrey Musuka, Phionah Lynn Atuhebwe, Ibrahim Dadari, Anisur Rahman Siddique
{"title":"Childhood vaccination catch-up and recovery plans for mitigating immunity gap post the COVID-19 pandemic: A case study of selected African countries","authors":"Abu Sadat Mohammad Sayem,&nbsp;Godfrey Musuka,&nbsp;Phionah Lynn Atuhebwe,&nbsp;Ibrahim Dadari,&nbsp;Anisur Rahman Siddique","doi":"10.1016/j.vaccine.2025.127328","DOIUrl":null,"url":null,"abstract":"<div><div>Since the start of the pandemic, routine vaccination has been delayed or suspended in many countries. Over one-third of countries have had continued disruptions to routine immunization programs in 2021. Since 2020, there has been an increase in zero-dose children, leading to a substantial immunity gap in many developing countries. Unvaccinated children have become susceptible to outbreaks due to missed immunization doses. Post-pandemic, measles, polio, and cholera outbreaks have occurred. To address this challenge, UNICEF, the World Health Organization (WHO), and the Global Alliance for Vaccines and Immunization (GAVI) have launched the Big Catch-up campaign to accelerate catch-up efforts, promote recovery, and enhance routine immunization programs in priority countries.</div><div>This paper outlines the prevalent challenges associated with reaching underserved children over the past four years, with a focus on the implementation of catch-up and recovery initiatives in 10 countries in two regions of Africa (East and Southern Africa (ESAR) and West and Central Africa Region (WCAR).</div><div>The study findings indicated that it was feasible to identify children who had not received any vaccinations in the country by utilizing various data sources documented in research papers. An initial obstacle encountered was locating these children within the community. Thematic analysis of the plans culminated in categorizing the primary challenge, initially involving vaccinating children over 2 years old per national policy. The subsequent difficulties encompassed identifying these children, generating demand for vaccinations among older children, and reporting on the population of children who had not received any vaccines. The strategies primarily revolved around fortifying the data system to capture these zero-dose children, implementing catch-up campaigns, and the Periodic Intensification of Routine Immunization (PIRI). The successful execution of the proposed strategies may diminish immunity gaps and reinforce routine immunization services, aligning with the IA2030 agenda.</div></div>","PeriodicalId":23491,"journal":{"name":"Vaccine","volume":"61 ","pages":"Article 127328"},"PeriodicalIF":4.5000,"publicationDate":"2025-05-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Vaccine","FirstCategoryId":"3","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S0264410X25006255","RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"IMMUNOLOGY","Score":null,"Total":0}
引用次数: 0

Abstract

Since the start of the pandemic, routine vaccination has been delayed or suspended in many countries. Over one-third of countries have had continued disruptions to routine immunization programs in 2021. Since 2020, there has been an increase in zero-dose children, leading to a substantial immunity gap in many developing countries. Unvaccinated children have become susceptible to outbreaks due to missed immunization doses. Post-pandemic, measles, polio, and cholera outbreaks have occurred. To address this challenge, UNICEF, the World Health Organization (WHO), and the Global Alliance for Vaccines and Immunization (GAVI) have launched the Big Catch-up campaign to accelerate catch-up efforts, promote recovery, and enhance routine immunization programs in priority countries.
This paper outlines the prevalent challenges associated with reaching underserved children over the past four years, with a focus on the implementation of catch-up and recovery initiatives in 10 countries in two regions of Africa (East and Southern Africa (ESAR) and West and Central Africa Region (WCAR).
The study findings indicated that it was feasible to identify children who had not received any vaccinations in the country by utilizing various data sources documented in research papers. An initial obstacle encountered was locating these children within the community. Thematic analysis of the plans culminated in categorizing the primary challenge, initially involving vaccinating children over 2 years old per national policy. The subsequent difficulties encompassed identifying these children, generating demand for vaccinations among older children, and reporting on the population of children who had not received any vaccines. The strategies primarily revolved around fortifying the data system to capture these zero-dose children, implementing catch-up campaigns, and the Periodic Intensification of Routine Immunization (PIRI). The successful execution of the proposed strategies may diminish immunity gaps and reinforce routine immunization services, aligning with the IA2030 agenda.
缓解COVID-19大流行后免疫差距的儿童疫苗接种追赶和恢复计划:对选定非洲国家的案例研究
自大流行开始以来,许多国家推迟或暂停了常规疫苗接种。2021年,超过三分之一的国家的常规免疫规划继续受到干扰。自2020年以来,零剂量儿童人数有所增加,导致许多发展中国家出现了巨大的免疫缺口。未接种疫苗的儿童由于错过免疫剂量而容易受到疫情的影响。大流行后,曾发生麻疹、脊髓灰质炎和霍乱疫情。为了应对这一挑战,联合国儿童基金会、世界卫生组织(世卫组织)和全球疫苗和免疫联盟(免疫联盟)发起了大规模追赶运动,以加快追赶努力,促进恢复,并加强重点国家的常规免疫规划。本文概述了在过去四年中与服务不足儿童相关的普遍挑战,重点介绍了非洲两个地区(东非和南部非洲(ESAR)和西非和中非地区(WCAR)的10个国家实施的追赶和恢复举措。研究结果表明,利用研究论文中记录的各种数据来源确定该国未接种任何疫苗的儿童是可行的。最初遇到的一个障碍是在社区内找到这些儿童。对这些计划进行专题分析的结果是对主要挑战进行分类,最初涉及根据国家政策为2岁以上儿童接种疫苗。随后的困难包括确定这些儿童,在年龄较大的儿童中产生接种疫苗的需求,以及报告未接种任何疫苗的儿童人数。这些战略主要围绕加强数据系统以捕获这些零剂量儿童、实施追赶运动以及定期加强常规免疫接种(PIRI)展开。拟议战略的成功实施可缩小免疫差距并加强常规免疫服务,与2030年可持续发展议程保持一致。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
求助全文
约1分钟内获得全文 求助全文
来源期刊
Vaccine
Vaccine 医学-免疫学
CiteScore
8.70
自引率
5.50%
发文量
992
审稿时长
131 days
期刊介绍: Vaccine is unique in publishing the highest quality science across all disciplines relevant to the field of vaccinology - all original article submissions across basic and clinical research, vaccine manufacturing, history, public policy, behavioral science and ethics, social sciences, safety, and many other related areas are welcomed. The submission categories as given in the Guide for Authors indicate where we receive the most papers. Papers outside these major areas are also welcome and authors are encouraged to contact us with specific questions.
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
确定
请完成安全验证×
copy
已复制链接
快去分享给好友吧!
我知道了
右上角分享
点击右上角分享
0
联系我们:info@booksci.cn Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术官方微信