Basma Beqqali, Joud Boutaleb, Basma Dghoughi, Lina Lasri, I Z I Zineb, Mohamed Bouchentouf, Tarik Salaheddine, Rachida Saouab, Meryem Edderai, Jamal Elfenni
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引用次数: 0
Abstract
A 70-year-old patient with a history of skull base osteomyelitis experienced slurred speech, dizziness, and coordination issues. He had been treated with both intravenous and oral metronidazole. Brain MRI revealed symmetrical areas of hyperintensity in the bilateral dentate nuclei, tectum, and splenium of the corpus callosum. These abnormalities nearly completely disappeared a few days after stopping the medication. Metronidazole, frequently used as an antiparasitic and antibacterial drug, can lead to neurotoxicity, particularly when used for extended periods. Symptoms generally improve after the drug is discontinued. MRI is vital for diagnosis and follow-up, as it detects specific changes in brain regions due to axonal swelling and increased water content.
期刊介绍：
Oxford Medical Case Reports (OMCR) is an open access, peer-reviewed online journal publishing original and educationally valuable case reports that expand the field of medicine. The journal covers all medical specialities including cardiology, rheumatology, nephrology, oncology, neurology, and reproduction, comprising a comprehensive resource for physicians in all fields and at all stages of training. Oxford Medical Case Reports deposits all articles in PubMed Central (PMC). Physicians and researchers can find your work through PubMed , helping you reach the widest possible audience. The journal is also indexed in the Web of Science Core Collection . Oxford Medical Case Reports publishes case reports under the following categories: Allergy Audiovestibular medicine Cardiology and cardiovascular systems Critical care medicine Dermatology Emergency medicine Endocrinology and metabolism Gastroenterology and hepatology Geriatrics and gerontology Haematology Immunology Infectious diseases and tropical medicine Medical disorders in pregnancy Medical ophthalmology Nephrology Neurology Oncology Paediatrics Pain Palliative medicine Pharmacology and pharmacy Psychiatry Radiology, nuclear medicine, and medical imaging Respiratory disorders Rheumatology Sexual and reproductive health Sports Medicine Substance abuse.
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