David Anuoluwapo Oyeniran, Tobiloba Samuel Olajide, Abayomi Oyeyemi Ajagbe, Abdulateef Ayoola Mobolaji
{"title":"Impact of sexuality on degenerative diseases.","authors":"David Anuoluwapo Oyeniran, Tobiloba Samuel Olajide, Abayomi Oyeyemi Ajagbe, Abdulateef Ayoola Mobolaji","doi":"10.1016/bs.pbr.2025.02.007","DOIUrl":null,"url":null,"abstract":"<p><p>Human sexuality is shaped by a complex interplay of biological, psychological, social, and cultural factors, influencing individual identity, behaviors, relationships, and sexual experience. Far from merely reflecting anatomical characteristics, sexuality encompasses emotional and sexual attraction toward individuals across gender spectrums, guided by factors including hormones, genetics, brain processes, and environmental influences. Societal norms and cultural beliefs also mold sexual expression, with diverse sexual identities being either embraced or stigmatized, impacting individual well-being. Sexual health, essential for mental and physical health, connects closely to brain morphology, function, and associated neural mechanisms. The hypothalamus and neurotransmitters like dopamine and oxytocin influence desire, feeling, and pleasure. Additionally, sexuality is linked with the progression and prevalence of degenerative diseases like Alzheimer's and Parkinson's. Sexual dysfunction relating to these diseases often emerges due to neurological changes, cognitive decline, and physical limitations. However, the feeling of sexual satisfaction can mitigate the impact of these diseases by promoting cognitive function, emotional intimacy, and stress reduction. Sexual activity in older adults is linked to better cardiovascular and cognitive health, emphasizing the broader health benefits of sexual well-being. Understanding sexuality across all stages of life, in both health and illness, is essential as it forms an integral part of general well-being and human existence.</p>","PeriodicalId":20598,"journal":{"name":"Progress in brain research","volume":"293 ","pages":"57-85"},"PeriodicalIF":0.0000,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Progress in brain research","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1016/bs.pbr.2025.02.007","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2025/2/28 0:00:00","PubModel":"Epub","JCR":"Q3","JCRName":"Neuroscience","Score":null,"Total":0}
引用次数: 0
Abstract
Human sexuality is shaped by a complex interplay of biological, psychological, social, and cultural factors, influencing individual identity, behaviors, relationships, and sexual experience. Far from merely reflecting anatomical characteristics, sexuality encompasses emotional and sexual attraction toward individuals across gender spectrums, guided by factors including hormones, genetics, brain processes, and environmental influences. Societal norms and cultural beliefs also mold sexual expression, with diverse sexual identities being either embraced or stigmatized, impacting individual well-being. Sexual health, essential for mental and physical health, connects closely to brain morphology, function, and associated neural mechanisms. The hypothalamus and neurotransmitters like dopamine and oxytocin influence desire, feeling, and pleasure. Additionally, sexuality is linked with the progression and prevalence of degenerative diseases like Alzheimer's and Parkinson's. Sexual dysfunction relating to these diseases often emerges due to neurological changes, cognitive decline, and physical limitations. However, the feeling of sexual satisfaction can mitigate the impact of these diseases by promoting cognitive function, emotional intimacy, and stress reduction. Sexual activity in older adults is linked to better cardiovascular and cognitive health, emphasizing the broader health benefits of sexual well-being. Understanding sexuality across all stages of life, in both health and illness, is essential as it forms an integral part of general well-being and human existence.
期刊介绍:
Progress in Brain Research is the most acclaimed and accomplished series in neuroscience. The serial is well-established as an extensive documentation of contemporary advances in the field. The volumes contain authoritative reviews and original articles by invited specialists. The rigorous editing of the volumes assures that they will appeal to all laboratory and clinical brain research workers in the various disciplines: neuroanatomy, neurophysiology, neuropharmacology, neuroendocrinology, neuropathology, basic neurology, biological psychiatry and the behavioral sciences.