Impact of sexuality on degenerative diseases.

4区 医学 Q3 Neuroscience
Progress in brain research Pub Date : 2025-01-01 Epub Date: 2025-02-28 DOI:10.1016/bs.pbr.2025.02.007
David Anuoluwapo Oyeniran, Tobiloba Samuel Olajide, Abayomi Oyeyemi Ajagbe, Abdulateef Ayoola Mobolaji
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引用次数: 0

Abstract

Human sexuality is shaped by a complex interplay of biological, psychological, social, and cultural factors, influencing individual identity, behaviors, relationships, and sexual experience. Far from merely reflecting anatomical characteristics, sexuality encompasses emotional and sexual attraction toward individuals across gender spectrums, guided by factors including hormones, genetics, brain processes, and environmental influences. Societal norms and cultural beliefs also mold sexual expression, with diverse sexual identities being either embraced or stigmatized, impacting individual well-being. Sexual health, essential for mental and physical health, connects closely to brain morphology, function, and associated neural mechanisms. The hypothalamus and neurotransmitters like dopamine and oxytocin influence desire, feeling, and pleasure. Additionally, sexuality is linked with the progression and prevalence of degenerative diseases like Alzheimer's and Parkinson's. Sexual dysfunction relating to these diseases often emerges due to neurological changes, cognitive decline, and physical limitations. However, the feeling of sexual satisfaction can mitigate the impact of these diseases by promoting cognitive function, emotional intimacy, and stress reduction. Sexual activity in older adults is linked to better cardiovascular and cognitive health, emphasizing the broader health benefits of sexual well-being. Understanding sexuality across all stages of life, in both health and illness, is essential as it forms an integral part of general well-being and human existence.

性对退行性疾病的影响。
人类的性行为是由生物、心理、社会和文化因素的复杂相互作用形成的,这些因素影响着个体的身份、行为、关系和性经验。性不仅仅反映了解剖学特征,它还包括对不同性别个体的情感和性吸引,受激素、基因、大脑过程和环境影响等因素的指导。社会规范和文化信仰也塑造了性表达,不同的性身份要么被接受,要么被污名化,从而影响个人福祉。性健康对身心健康至关重要,与大脑形态、功能和相关神经机制密切相关。下丘脑和多巴胺和催产素等神经递质影响欲望、感觉和快乐。此外,性行为与阿尔茨海默氏症和帕金森氏症等退行性疾病的进展和流行有关。与这些疾病相关的性功能障碍通常是由于神经系统的改变、认知能力的下降和身体的限制而出现的。然而,性满足的感觉可以通过促进认知功能、情感亲密和减轻压力来减轻这些疾病的影响。老年人的性活动与更好的心血管和认知健康有关,强调了性健康对更广泛的健康益处。理解生命各个阶段的性行为,无论是健康还是疾病,都是至关重要的,因为它构成了总体福祉和人类生存的一个组成部分。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
Progress in brain research
Progress in brain research 医学-神经科学
CiteScore
5.20
自引率
0.00%
发文量
174
审稿时长
6-12 weeks
期刊介绍: Progress in Brain Research is the most acclaimed and accomplished series in neuroscience. The serial is well-established as an extensive documentation of contemporary advances in the field. The volumes contain authoritative reviews and original articles by invited specialists. The rigorous editing of the volumes assures that they will appeal to all laboratory and clinical brain research workers in the various disciplines: neuroanatomy, neurophysiology, neuropharmacology, neuroendocrinology, neuropathology, basic neurology, biological psychiatry and the behavioral sciences.
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