Impact of positive feelings and negative feelings on brain cell regeneration and degeneration.

Abstract

Brain cells intentionally break their DNA as a crucial step in memory formation and learning. This process allows for the expression of specific genes that are essential for these cognitive functions. While our cells are generally adept at repairing this self-inflicted DNA damage, the efficiency of this repair mechanism can decline with age or due to certain genetic factors. The deliberate DNA breakage in neurons enables the activation of rapid response genes, which in turn trigger broader transcriptional programs supporting various behaviors, including learning and memory. This process is a normal part of cellular function and gene expression. However, neurological disorders, certain syndromes, and the aging process can impair this DNA repair ability. When cells struggle to mend the intentional DNA breaks, it can lead to cellular weakening and eventual degeneration. The subsequent discussion will explore how positive and negative emotions influence the processes of brain cell regeneration and degradation.