Impact of functional status and biomarkers on hospital costs and readmission rates in geriatric patients: An observational study with comprehensive geriatric assessment.

IF 2.9 3区 综合性期刊 Q1 MULTIDISCIPLINARY SCIENCES
PLoS ONE Pub Date : 2025-05-29 eCollection Date: 2025-01-01 DOI:10.1371/journal.pone.0324465
Irene Simonetti, Stefano Landi, Chiara Leardini, Anna Giani, Arianna Bortolani, Francesco Fantin
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Abstract

This study aimed to analyze the association between functional status, biomarkers, and hospitalization characteristics on costs and the probability of re-admission at 30 and 180 days in geriatric patients. It is used an observational design with both administrative data and additional clinical data not usually collected. Multivariate linear regression for hospitalization costs and multivariate logistic regressions for readmissions were used. Variables studied included the Barthel Index, Charlson index, albumin and blood pressure levels, previous hospitalizations, length of stay (LoS), and controls. Data from 953 patients aged over 65, admitted to the Geriatric ward between September 1st, 2018, and December 31st, 2019, were analyzed. The Charlson comorbidity index, number of comorbidities, and LoS were positively related to hospitalization costs. Previous hospitalizations and LoS were the main predictors of readmission. Systolic blood pressure was negatively associated with the odds of re-admission but showed no association with hospital costs. Higher functional status, as measured by the Barthel index, was linked to lower odds of unplanned hospitalization but was not statistically significant for costs. Functional status and biomarkers had moderate effects on costs and readmission odds. These findings can aid in early healthcare planning and resource management, providing valuable information for prioritizing patients and designing cost-effective care interventions.

功能状态和生物标志物对老年患者住院费用和再入院率的影响:一项综合老年评估的观察性研究
本研究旨在分析老年患者的功能状态、生物标志物和住院特征与费用和30天和180天再入院概率之间的关系。它采用观察性设计,包括通常不收集的行政数据和附加临床数据。住院费用采用多元线性回归,再入院采用多元逻辑回归。研究的变量包括Barthel指数、Charlson指数、白蛋白和血压水平、既往住院情况、住院时间(LoS)和对照。分析了2018年9月1日至2019年12月31日期间入住老年病房的953名65岁以上患者的数据。Charlson合并症指数、合并症数量和LoS与住院费用呈正相关。既往住院和住院时间是再入院的主要预测因素。收缩压与再次入院的几率呈负相关,但与医院费用无关。以Barthel指数衡量,较高的功能状态与较低的计划外住院几率有关,但在费用方面没有统计学意义。功能状态和生物标志物对费用和再入院几率有中等影响。这些发现有助于早期医疗保健计划和资源管理,为优先考虑患者和设计具有成本效益的护理干预措施提供有价值的信息。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
PLoS ONE
PLoS ONE 生物-生物学
CiteScore
6.20
自引率
5.40%
发文量
14242
审稿时长
3.7 months
期刊介绍: PLOS ONE is an international, peer-reviewed, open-access, online publication. PLOS ONE welcomes reports on primary research from any scientific discipline. It provides: * Open-access—freely accessible online, authors retain copyright * Fast publication times * Peer review by expert, practicing researchers * Post-publication tools to indicate quality and impact * Community-based dialogue on articles * Worldwide media coverage
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