Limbal stem cell deficiency: a dreaded complication of chickenpox in children.

IF 0.5 Q3 MEDICINE, GENERAL & INTERNAL

Oxford Medical Case Reports Pub Date : 2025-05-28 eCollection Date: 2025-05-01 DOI:10.1093/omcr/omaf037

Oumayma Elmansouri, Assia Lemkhoudem, Houda Bezza, Houssaine Ait Lhaj, Mohamed Kriet, Fouad Elasri

引用次数: 0

Abstract

We report a rare case of Limbal Stem Cell Deficiency (LSCD) in a 10-year-old child following chickenpox. The child presented with persistent ocular symptoms, including pain, redness, and photophobia, two months after the resolution of systemic chickenpox. Ophthalmic examination revealed conjunctival hyperemia, 360° conjunctivalization, corneal neovascularization, and an epithelial defect. LSCD, characterized by corneal neovascularization and conjunctivalization, can occur after viral infections, including herpes zoster. To our knowledge, this is the first reported case of LSCD following chickenpox in a child. Early recognition and collaborative care between pediatricians and ophthalmologists are essential for effective management.

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角膜缘干细胞缺乏：儿童水痘的可怕并发症。

我们报告一例罕见的角膜缘干细胞缺乏症（LSCD）在一个10岁的儿童后水痘。全身性水痘消退2个月后，患儿出现持续眼部症状，包括疼痛、红肿和畏光。眼科检查显示结膜充血，360°结膜化，角膜新生血管和上皮缺损。LSCD以角膜新生血管和结膜形成为特征，可在病毒感染后发生，包括带状疱疹。据我们所知，这是第一例报道的儿童水痘后LSCD病例。儿科医生和眼科医生之间的早期识别和合作护理是有效管理的必要条件。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Oxford Medical Case Reports MEDICINE, GENERAL & INTERNAL-

CiteScore

0.90

自引率

0.00%

发文量

125

审稿时长

19 weeks

期刊介绍： Oxford Medical Case Reports (OMCR) is an open access, peer-reviewed online journal publishing original and educationally valuable case reports that expand the field of medicine. The journal covers all medical specialities including cardiology, rheumatology, nephrology, oncology, neurology, and reproduction, comprising a comprehensive resource for physicians in all fields and at all stages of training. Oxford Medical Case Reports deposits all articles in PubMed Central (PMC). Physicians and researchers can find your work through PubMed , helping you reach the widest possible audience. The journal is also indexed in the Web of Science Core Collection . Oxford Medical Case Reports publishes case reports under the following categories: Allergy Audiovestibular medicine Cardiology and cardiovascular systems Critical care medicine Dermatology Emergency medicine Endocrinology and metabolism Gastroenterology and hepatology Geriatrics and gerontology Haematology Immunology Infectious diseases and tropical medicine Medical disorders in pregnancy Medical ophthalmology Nephrology Neurology Oncology Paediatrics Pain Palliative medicine Pharmacology and pharmacy Psychiatry Radiology, nuclear medicine, and medical imaging Respiratory disorders Rheumatology Sexual and reproductive health Sports Medicine Substance abuse.