Case Report: Acute hepatitis A virus infection presenting with direct antiglobulin test-negative autoimmune hemolytic anemia and α-thalassemia trait.

Q2 Pharmacology, Toxicology and Pharmaceutics

F1000Research Pub Date : 2025-04-15 eCollection Date: 2024-01-01 DOI:10.12688/f1000research.156586.2

Habiba Debbabi, Eya Chakroun, Hajer Hassine, Hela Kchir, Dhouha Cherif, Haythem Yacoub, Nadia Maamouri

引用次数: 0

Abstract

Reports from the literature have discussed patients presenting Hepatitis A virus infection with hemolytic anemia, specifically with glucose-6-phosphate dehydrogenase deficiency. However, autoimmune hemolytic anemia (AIHA) has been rarely reported. We present a challenging case of Coombs-negative hemolytic anemia as initial manifestation of hepatitis A virus infection in a silent carrier of α-thalassemia.

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病例报告：急性甲型肝炎病毒感染表现为直接抗球蛋白试验阴性的自身免疫性溶血性贫血和α-地中海贫血特征。

文献报道讨论了甲型肝炎病毒感染合并溶血性贫血的患者，特别是葡萄糖-6-磷酸脱氢酶缺乏症。然而，自身免疫性溶血性贫血（AIHA）鲜有报道。我们提出了一个具有挑战性的病例，库姆斯阴性溶血性贫血作为α-地中海贫血沉默携带者甲型肝炎病毒感染的初始表现。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

F1000Research Pharmacology, Toxicology and Pharmaceutics-Pharmacology, Toxicology and Pharmaceutics (all)

CiteScore

5.00

自引率

0.00%

发文量

1646

审稿时长

1 weeks

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