Outside Front Cover: Biomimetic Hierarchical Construction of Anti-Tumor Polyoxopalladates for Cancer Therapy (Angew. Chem. 23/2025)

Yue Zhao, Zheran Liu, Zijian Qin, Qinlong Wen, Jing Du, Xiang-Yu Ren, Chao-Qin Chen, Xingchen Peng, Ulrich Kortz, Peng Yang
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引用次数: 0

Abstract

Following the construction scheme of biomacromolecules, the hierarchical assembly of polyoxometalates via an overall management of covalent and non-covalent bindings is full of challenges and surprises. In their Research Article (e202505564), Peng Yang et al. achieved a highly ordered structural evolution of polyoxopalladates from monomer via dimer to supramolecular aggregates, along with an enhanced anti-tumor activity via DNA damage for cancer treatment.

Abstract Image

外封面:用于癌症治疗的抗肿瘤多氧藻酸盐的仿生分层结构。化学23/2025)
根据生物大分子的构建方案,通过对共价和非共价结合的整体管理来分层组装多金属氧酸盐充满了挑战和惊喜。在他们的研究文章(e202505564)中,彭阳等人实现了多氧藻酸盐从单体到二聚体到超分子聚集体的高度有序的结构进化,并通过DNA损伤增强了抗肿瘤活性,用于癌症治疗。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
Angewandte Chemie
Angewandte Chemie 化学科学, 有机化学, 有机合成
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