Preretinal Hyperreflective Dots: A novel OCT Sign Associated With The Development Of Epiretinal Membrane After Vitrectomy For Rhegmatogenous Retinal Detachment.

IF 2.3 2区医学 Q2 OPHTHALMOLOGY

Retina-The Journal of Retinal and Vitreous Diseases Pub Date : 2025-05-27 DOI:10.1097/IAE.0000000000004540

Bayram Mhibik, Federico Bernabei, Marco Pellegrini, Antoine Constant, Cassem Azri, Pauline Eymard, Maria Angela Romeo, Frederic Azan, Giuseppe Giannaccare, Pierre-Raphael Rothschild

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引用次数: 0

Abstract

Purpose: To investigate the association between preretinal hyperreflective dots (PHD) with the occurrence of epiretinal membrane (ERM) following pars plana vitrectomy (PPV) for rhegmatogenous retinal detachment (RRD).

Methods: This retrospective study included patients who underwent PPV for RRD at Ophtalmopôle de Paris. Optical coherence tomography (OCT) scans were acquired at 1, 3, 6 months and 1 year post-surgery. PHD were defined as point-like hyperreflective deposits on the inner retinal surface on the first postoperative OCT. The association between PHD and ERM was evaluated using logistic regression and Kaplan-Meier analysis.

Results: Of 894 patients who underwent vitrectomy for RRD, 417 were included in the analysis. Univariate analysis showed significant associations between ERM occurrence and macula-off RRD (P=0.043), number of retinal tears (P=0.002), use of cryopexy (P=0.012), C2F6 tamponade (P=0.045), and presence of PHD on OCT (P<0.001). On multivariate analysis, presence of PHD (P<0.001) and use of cryopexy (P=0.013) were significant predictors of ERM. Kaplan-Meier analysis indicated that the cumulative probability of developing an ERM at 6 months was 4% in patients without PHD and 26% in patients with PHD (P<0.001).

Conclusion: PHD are associated with the occurrence of ERM following vitrectomy for RRD.

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视网膜前高反射点：一种与孔源性视网膜脱离玻璃体切除术后视网膜上膜发育相关的新型OCT征象。

目的：探讨孔源性视网膜脱离（RRD）玻璃体切除术（PPV）后视网膜前高反射点（PHD）与视网膜前膜（ERM）发生的关系。方法：这项回顾性研究纳入了在Ophtalmopôle de Paris接受PPV治疗RRD的患者。分别于术后1、3、6个月和1年进行光学相干断层扫描（OCT）。dr被定义为术后第一次oct视网膜内表面的点状高反射性沉积物。采用logistic回归和Kaplan-Meier分析评估PHD与ERM之间的关系。结果：在894例因RRD行玻璃体切除术的患者中，有417例纳入分析。单因素分析显示，ERM的发生与黄斑脱落的RRD （P=0.043）、视网膜撕裂数（P=0.002）、冷冻冷冻（P=0.012）、C2F6填塞（P=0.045）、OCT上是否有PHD存在显著相关(P)。结论：PHD与RRD玻璃体切除术后ERM的发生有关。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Retina-The Journal of Retinal and Vitreous Diseases 医学-眼科学

CiteScore

5.70

自引率

9.10%

发文量

554

审稿时长

3-6 weeks

期刊介绍： RETINA® focuses exclusively on the growing specialty of vitreoretinal disorders. The Journal provides current information on diagnostic and therapeutic techniques. Its highly specialized and informative, peer-reviewed articles are easily applicable to clinical practice. In addition to regular reports from clinical and basic science investigators, RETINA® publishes special features including periodic review articles on pertinent topics, special articles dealing with surgical and other therapeutic techniques, and abstract cards. Issues are abundantly illustrated in vivid full color. Published 12 times per year, RETINA® is truly a “must have” publication for anyone connected to this field.