Malnutrition in Colorectal Cancer Patients: Association with the Lack of Eating Motivation and Inappropriate Diet.

Q2 Medicine

Asian Pacific Journal of Cancer Prevention Pub Date : 2025-05-01 DOI:10.31557/APJCP.2025.26.5.1661

Le Thi Ngoc Anh, To Gia Kien, Nguyen Van Tuan, Tran Thi Anh Tuong, Juyeon Ko, Phan Tan Dan, Jaelim Cho, Nguyen Van Tap

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引用次数: 0

Abstract

Objective: Colorectal cancer (CRC) significantly contributes to cancer-related mortality in Vietnam. Notably, malnutrition, rather than cancer itself, accounts for one-fifth of the deaths among cancer patients. Therefore, understanding the nutritional status and related factors among CRC patients is essential. We aimed to investigate the nutritional status and related factors in CRC in Vietnam.

Methods: This cross-sectional study, conducted from October 2022 to April 2023, included CRCs of both sexes aged ≥18 years. Data collection involved face-to-face interviews, anthropometric assessments, and medical record reviews. Nutritional status was evaluated using the Patient-Generated Subjective Global Assessment (PG-SGA). Multivariable logistic regression was used to identify malnutrition-related factors.

Results: In total, 388 patients were included (median age, 60.0 years, [IQR: 51.0-66.0 years]; men, 57.7%). The prevalence of malnutrition was 87.9% (95%CI: 84.6-91.1), and urgent nutritional intervention was needed in 64.7% of participants. Malnutrition-associated factors included lack of eating motivation (OR=8.76, 95%CI: 1.81-42.38), dieting for fear of cancer cell growth (OR=3.82, 95%CI: 1.27-11.52), gastrointestinal symptoms (OR=5.38, 95%CI: 1.76-16.45), daily energy intake <25kcal/kg (OR=7.02, 95%CI: 1.70-28.99), protein ≤ 1g/kg (OR=5.21, 95%CI: 1.32-20.60), fat <18% of total energy intake (OR=3.13, 95%CI: 1.02-9.57), mean corpuscular volume <85fL (OR=4.74, 95%CI: 1.11-20.22), and total lymphocyte count ≤1700 lymphocytes/mm3 (OR=4.06, 95%CI: 1.22-13.50). Additionally, a 1-kg increase in dominant hand strength reduced the risk of malnutrition by 4% (OR=0.96, 95%CI: 0.93-0.99).

Conclusion: The high prevalence of malnutrition among CRCs in Vietnam necessitates nutritional intervention. The main contributors include loss of eating motivation and inadequate dietary intake.

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结直肠癌患者营养不良：与缺乏饮食动机和不适当饮食有关。

目的：结直肠癌（CRC）是越南癌症相关死亡率的重要因素。值得注意的是，五分之一的癌症患者死亡原因是营养不良，而不是癌症本身。因此，了解结直肠癌患者的营养状况及其相关因素至关重要。我们旨在调查越南结直肠癌患者的营养状况及相关因素。方法：这项横断面研究于2022年10月至2023年4月进行，包括年龄≥18岁的男女crc。数据收集包括面对面访谈、人体测量评估和医疗记录审查。采用患者主观整体评估（PG-SGA）评估营养状况。采用多变量logistic回归确定营养不良相关因素。结果：共纳入388例患者(中位年龄60.0岁，[IQR: 51.0-66.0岁]；人,57.7%)。营养不良患病率为87.9% (95%CI: 84.6-91.1)， 64.7%的参与者需要紧急营养干预。营养不良相关因素包括缺乏饮食动机（OR=8.76, 95%CI: 1.81-42.38）、因害怕癌细胞生长而节食（OR=3.82, 95%CI: 1.27-11.52）、胃肠道症状（OR=5.38, 95%CI: 1.76-16.45）、每日能量摄入。结论：越南crc中营养不良发生率高，需要进行营养干预。主要原因包括饮食动机的丧失和饮食摄入不足。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Asian Pacific Journal of Cancer Prevention 医学-肿瘤学

CiteScore

2.80

自引率

0.00%

发文量

779

审稿时长

3 months

期刊介绍： Cancer is a very complex disease. While many aspects of carcinoge-nesis and oncogenesis are known, cancer control and prevention at the community level is however still in its infancy. Much more work needs to be done and many more steps need to be taken before effective strategies are developed. The multidisciplinary approaches and efforts to understand and control cancer in an effective and efficient manner, require highly trained scientists in all branches of the cancer sciences, from cellular and molecular aspects to patient care and palliation. The Asia Pacific Organization for Cancer Prevention (APOCP) and its official publication, the Asia Pacific Journal of Cancer Prevention (APJCP), have served the community of cancer scientists very well and intends to continue to serve in this capacity to the best of its abilities. One of the objectives of the APOCP is to provide all relevant and current scientific information on the whole spectrum of cancer sciences. They aim to do this by providing a forum for communication and propagation of original and innovative research findings that have relevance to understanding the etiology, progression, treatment, and survival of patients, through their journal. The APJCP with its distinguished, diverse, and Asia-wide team of editors, reviewers, and readers, ensure the highest standards of research communication within the cancer sciences community across Asia as well as globally. The APJCP publishes original research results under the following categories: -Epidemiology, detection and screening. -Cellular research and bio-markers. -Identification of bio-targets and agents with novel mechanisms of action. -Optimal clinical use of existing anti-cancer agents, including combination therapies. -Radiation and surgery. -Palliative care. -Patient adherence, quality of life, satisfaction. -Health economic evaluations.