Nicholas Strowbridge, David R Vieites, Michael G Ritchie, Kathryn R Elmer
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引用次数: 0
Abstract
Due to its high variation and its diversity of functional roles, animal colouration has long been a fascinating phenotype for geneticists. While the loci underpinning colour are relatively well known, there remain components of unexplained variation. The contribution of DNA and RNA methylation to these molecular mechanisms of colouration is only now being explored. Recent research has shown that DNA (m5C) methylation plays a role in plastic colouration change, the development of colour, and adult intra- and interindividual colouration differences. Studies on RNA (m6A) methylation are few but suggest that it also contributes to colour differences. Emerging advances in native DNA and RNA sequencing will allow a novel understanding of methylation contributions to colour evolution and development.
期刊介绍:
Launched in 1985, Trends in Genetics swiftly established itself as a "must-read" for geneticists, offering concise, accessible articles covering a spectrum of topics from developmental biology to evolution. This reputation endures, making TiG a cherished resource in the genetic research community. While evolving with the field, the journal now embraces new areas like genomics, epigenetics, and computational genetics, alongside its continued coverage of traditional subjects such as transcriptional regulation, population genetics, and chromosome biology.
Despite expanding its scope, the core objective of TiG remains steadfast: to furnish researchers and students with high-quality, innovative reviews, commentaries, and discussions, fostering an appreciation for advances in genetic research. Each issue of TiG presents lively and up-to-date Reviews and Opinions, alongside shorter articles like Science & Society and Spotlight pieces. Invited from leading researchers, Reviews objectively chronicle recent developments, Opinions provide a forum for debate and hypothesis, and shorter articles explore the intersection of genetics with science and policy, as well as emerging ideas in the field. All articles undergo rigorous peer-review.