Brief guide to assays for measuring health parameters using Caenorhabditis elegans

IF 3.7 3区生物学 Q2 BIOCHEMISTRY & MOLECULAR BIOLOGY

Molecules and Cells Pub Date : 2025-05-26 DOI:10.1016/j.mocell.2025.100233

Seungjae Hwang, Jongsun Lee, Seung-Jae V. Lee

引用次数: 0

Abstract

Assessing health parameters is essential for understanding the decline of physiological functions during aging. The nematode Caenorhabditis elegans serves as a powerful model in aging research. This paper introduces representative methods for evaluating health parameters using C. elegans and provides quantitative indicators of functional declines during aging. This manuscript will be useful for researchers unfamiliar with healthspan studies using C. elegans and may help perform physiological experiments for healthy aging.

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用秀丽隐杆线虫测定健康参数的试验指南。

评估健康参数是了解衰老过程中生理功能下降的必要条件。秀丽隐杆线虫是衰老研究中一个强有力的模型。介绍了秀丽隐杆线虫健康参数评价的代表性方法，给出了衰老过程中功能衰退的定量指标。这篇论文将对不熟悉秀丽隐杆线虫健康寿命研究的研究人员有用，并可能有助于进行健康衰老的生理实验。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Molecules and Cells 生物-生化与分子生物学

CiteScore

6.60

自引率

10.50%

发文量

审稿时长

2.3 months

期刊介绍： Molecules and Cells is an international on-line open-access journal devoted to the advancement and dissemination of fundamental knowledge in molecular and cellular biology. It was launched in 1990 and ISO abbreviation is "Mol. Cells". Reports on a broad range of topics of general interest to molecular and cell biologists are published. It is published on the last day of each month by the Korean Society for Molecular and Cellular Biology.