High Rates of Bacteremia and Fluoroquinolone Resistance During an Outbreak of Shigellosis Among People Experiencing Homelessness and Opioid Use Disorder in Philadelphia, Pennsylvania.

IF 3.8 4区医学 Q2 IMMUNOLOGY

Open Forum Infectious Diseases Pub Date : 2025-05-16 eCollection Date: 2025-05-01 DOI:10.1093/ofid/ofaf296

Eleanor Stedman, Andrea Molin, Valencia Oglesby, Erin Torpey, Stephanie Spivack, Kaede V Sullivan, Sara Schultz

引用次数: 0

Abstract

In 2023, Philadelphia reported an outbreak of Shigella flexneri infections. We evaluated all patients hospitalized in our health system with shigellosis during this outbreak. Sixty-seven patients were hospitalized, and 21 (31.3%) were bacteremic. Trimethoprim-sulfamethoxazole was the only antibiotic with reliable susceptibility. Most patients had housing insecurity and opioid use disorder.

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宾夕法尼亚州费城无家可归和阿片类药物使用障碍人群中志贺氏菌病暴发期间菌血症和氟喹诺酮类药物耐药性高

2023年，费城报告了一次福氏志贺氏菌感染的爆发。我们评估了本次疫情期间在我国卫生系统中因志贺氏菌病住院的所有患者。67例住院，21例（31.3%）为菌血症。甲氧苄啶-磺胺甲恶唑是唯一具有可靠药敏的抗生素。大多数患者有住房不安全感和阿片类药物使用障碍。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Open Forum Infectious Diseases Medicine-Neurology (clinical)

CiteScore

6.70

自引率

4.80%

发文量

630

审稿时长

9 weeks

期刊介绍： Open Forum Infectious Diseases provides a global forum for the publication of clinical, translational, and basic research findings in a fully open access, online journal environment. The journal reflects the broad diversity of the field of infectious diseases, and focuses on the intersection of biomedical science and clinical practice, with a particular emphasis on knowledge that holds the potential to improve patient care in populations around the world. Fully peer-reviewed, OFID supports the international community of infectious diseases experts by providing a venue for articles that further the understanding of all aspects of infectious diseases.