Adrianna Bargielska, Anna Wasilewska, Agnieszka Rybi-Szumińska
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引用次数: 0
Abstract
Acute kidney injury (AKI) affects a significant percentage of the pediatric population. Currently, the diagnosis of AKI in children still uses traditional laboratory methods (ex. creatinine or urea serum concentration and measurement of urine output). It has significant limitations. Early stages of AKI in children may be almost asymptomatic. In-depth assessment with the pRIFLE scale is helpful, but requires bladder catheterization and precise monitoring of hourly diuresis, as well as multiple blood draws to determine changes in creatinine concentration and estimate glomerular filtration rate (eGFR). The diagnostic methods lack a marker that would the early and potentially reversible phase of kidney damage. This paper reviews recent data on selected AKI markers in children, including their diagnostic and prognostic potential.
期刊介绍:
Italian Journal of Pediatrics is an open access peer-reviewed journal that includes all aspects of pediatric medicine. The journal also covers health service and public health research that addresses primary care issues.
The journal provides a high-quality forum for pediatricians and other healthcare professionals to report and discuss up-to-the-minute research and expert reviews in the field of pediatric medicine. The journal will continue to develop the range of articles published to enable this invaluable resource to stay at the forefront of the field.
Italian Journal of Pediatrics, which commenced in 1975 as Rivista Italiana di Pediatria, provides a high-quality forum for pediatricians and other healthcare professionals to report and discuss up-to-the-minute research and expert reviews in the field of pediatric medicine. The journal will continue to develop the range of articles published to enable this invaluable resource to stay at the forefront of the field.