Reconsidering the management and prognostic implications of myoclonus and status epilepticus post-cardiac arrest.

IF 3.7 3区医学 Q1 CLINICAL NEUROLOGY

Clinical Neurophysiology Pub Date : 2025-05-17 DOI:10.1016/j.clinph.2025.2110754

Pia De Stefano

引用次数: 0

Abstract

Status epilepticus and myoclonus are frequent findings in post-cardiac arrest patients. While traditionally associated with poor outcomes, emerging evidence highlights scenarios where aggressive and tailored interventions may alter prognosis. This paper critically evaluates the definitions, diagnostic challenges, and therapeutic strategies for SE and myoclonus in this context. It highlights the necessity of standardized EEG-based evaluations to refine prognostic models and guide treatments. The findings advocate for a nuanced approach integrating EEG background and patterns, their evolution, and clinical assessments, offering a path forward in addressing the complexities of post-cardiac arrest encephalopathy.

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重新考虑心脏骤停后肌阵挛和癫痫持续状态的处理和预后意义。

癫痫持续状态和肌阵挛是心脏骤停后患者的常见症状。虽然传统上与不良结果相关，但新出现的证据强调了积极和量身定制的干预措施可能改变预后的情况。本文在此背景下批判性地评估了SE和肌阵挛的定义、诊断挑战和治疗策略。它强调了标准化的基于脑电图的评估，以完善预后模型和指导治疗的必要性。研究结果提倡一种细致入微的方法，将脑电图背景和模式、它们的演变和临床评估结合起来，为解决心脏骤停后脑病的复杂性提供了一条前进的道路。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Clinical Neurophysiology 医学-临床神经学

CiteScore

8.70

自引率

6.40%

发文量

932

审稿时长

59 days

期刊介绍： As of January 1999, The journal Electroencephalography and Clinical Neurophysiology, and its two sections Electromyography and Motor Control and Evoked Potentials have amalgamated to become this journal - Clinical Neurophysiology. Clinical Neurophysiology is the official journal of the International Federation of Clinical Neurophysiology, the Brazilian Society of Clinical Neurophysiology, the Czech Society of Clinical Neurophysiology, the Italian Clinical Neurophysiology Society and the International Society of Intraoperative Neurophysiology.The journal is dedicated to fostering research and disseminating information on all aspects of both normal and abnormal functioning of the nervous system. The key aim of the publication is to disseminate scholarly reports on the pathophysiology underlying diseases of the central and peripheral nervous system of human patients. Clinical trials that use neurophysiological measures to document change are encouraged, as are manuscripts reporting data on integrated neuroimaging of central nervous function including, but not limited to, functional MRI, MEG, EEG, PET and other neuroimaging modalities.