Synthesis of pyrrolo[3,2-d]pyrimidine-2,4(3H)-diones by domino C-N coupling/hydroamination reactions.

IF 2.1 4区化学 Q2 CHEMISTRY, ORGANIC

Beilstein Journal of Organic Chemistry Pub Date : 2025-05-22 eCollection Date: 2025-01-01 DOI:10.3762/bjoc.21.82

Ruben Manuel Figueira de Abreu, Robin Tiedemann, Peter Ehlers, Peter Langer

引用次数: 0

Abstract

A variety of pyrrolo[3,2-d]pyrimidine-2,4(3H)-diones were prepared by a combination of Sonogashira reaction and subsequent cyclization by domino C-N coupling/hydroamination reaction. The optical properties (UV-vis absorption and fluorescence) depend on the substitution pattern of the compounds.

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用多米诺C-N偶联/氢胺化反应合成吡咯[3,2-d]嘧啶-2,4(3H)-二酮

通过Sonogashira反应和随后的多米诺C-N偶联/氢胺化反应合成了多种吡咯[3,2-d]嘧啶-2,4(3H)-二酮。光学性质（紫外-可见吸收和荧光）取决于化合物的取代模式。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Beilstein Journal of Organic Chemistry 化学-有机化学

CiteScore

4.90

自引率

3.70%

发文量

167

审稿时长

1.4 months

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