Advanced ActivePure Technology: The Opportunity for Risk Assessment Using Murine Model

IF 4.3 2区环境科学与生态学 Q1 CONSTRUCTION & BUILDING TECHNOLOGY

Indoor air Pub Date : 2025-05-30 DOI:10.1155/ina/9916852

Tomasz Niemiec, Wiesław Świderek, Małgorzata Rzepkowska, Magdalena Fajkowska, Marta Gajewska, Karolina Wnęk-Auguścik, Malwina Sosnowska, Magdalena Matusiewicz, Andrzej Łozicki, Klara Piotrowska

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Abstract

This study evaluates the effects of Advanced ActivePure technology, a photocatalytic air purification system, on the health status of mice housed in a controlled environment. This novel technology is promising due to its ability to eliminate the risk of ozone release into the environment, making it safer compared to other photocatalytic oxidation technologies. Utilizing 300 6-month-old mice over a period of 3 months, this research investigated various health parameters, including haematological, serum biochemical, redox, and inflammatory indicators. The experiment demonstrated no significant alteration in the majority of tested parameters between the control and Advanced ActivePure-exposed groups. Until now, no study has analyzed the health safety of living organisms exposed to Advanced ActivePure in such a detailed manner. Histopathological analyses of nasal and eye tissues showed no adverse changes attributable to Advanced ActivePure exposure. These findings suggest that Advanced ActivePure technology does not negatively impact the overall health of mice, including biochemical markers and respiratory histopathology.

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先进的ActivePure技术：利用小鼠模型进行风险评估的机会

本研究评估了Advanced ActivePure技术（一种光催化空气净化系统）对置于受控环境中的小鼠健康状况的影响。这项新技术很有前景，因为它能够消除臭氧释放到环境中的风险，与其他光催化氧化技术相比，它更安全。在3个月的时间里，本研究利用300只6个月大的小鼠，研究了各种健康参数，包括血液学、血清生化、氧化还原和炎症指标。实验表明，在对照组和Advanced activepure暴露组之间，大多数测试参数没有显着变化。到目前为止，还没有研究以如此详细的方式分析暴露于Advanced ActivePure的生物体的健康安全性。对鼻和眼组织的组织病理学分析显示，暴露于Advanced ActivePure后没有出现不良变化。这些发现表明，Advanced ActivePure技术不会对小鼠的整体健康产生负面影响，包括生化指标和呼吸组织病理学。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Indoor air 环境科学-工程：环境

CiteScore

10.80

自引率

10.30%

发文量

175

审稿时长

3 months

期刊介绍： The quality of the environment within buildings is a topic of major importance for public health. Indoor Air provides a location for reporting original research results in the broad area defined by the indoor environment of non-industrial buildings. An international journal with multidisciplinary content, Indoor Air publishes papers reflecting the broad categories of interest in this field: health effects; thermal comfort; monitoring and modelling; source characterization; ventilation and other environmental control techniques. The research results present the basic information to allow designers, building owners, and operators to provide a healthy and comfortable environment for building occupants, as well as giving medical practitioners information on how to deal with illnesses related to the indoor environment.