Epithelial-myoepithelial carcinoma: Retrospective analysis of the case series from a reference center in São Paulo, Brazil

IF 1.7 4区医学 Q2 OTORHINOLARYNGOLOGY

Brazilian Journal of Otorhinolaryngology Pub Date : 2025-05-29 DOI:10.1016/j.bjorl.2025.101615

Gabriela Miglioranza Gonçalves Luccas , Kim Soares Marinho , Lara Caroline Cardoso , Maria Paula Spegiorin de Oliveira , Renato Nobutaka Gotoda , Dorival de Carlucci Junior , Luiz Paulo Kowalski

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引用次数: 0

Abstract

Objective

Given the recent increase in diagnoses in our service, a referral center in São Paulo, this study aims to analyze the case series at this center and compare it with the existing literature. The objective is to comprehend the characteristics and prognosis of this disease and provide insights to enhance its treatment.

Methods

Confirmed cases of EMC were selected at the Hospital das Clínicas da FMUSP between 2011 and 2021. Fourteen cases were screened and subjected to retrospective analysis of medical records for data collection.

Results

The analysis covered patient and disease characteristics. Of the total, 64.3% were female, with an average age of 71.33 years. The parotid gland was the predominant primary site (92.8%). Concerning staging, there was a significant prevalence in stages III and IVa. Among the cases, 12 underwent surgery, and eight patients received adjuvant therapy.

Conclusion

Despite EMC being a low-grade neoplasm, our case series, while aligning with much of the existing literature, revealed a more advanced presentation. This raises questions about whether this aggressiveness is due to late diagnosis or whether the neoplasm is less indolent than presumed.

Level of evidence

Level IV.

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上皮-肌上皮癌：来自巴西圣保罗一家参考中心的病例系列回顾性分析

目的考虑到最近在我们圣保罗转诊中心的诊断增加，本研究旨在分析该中心的病例系列，并与现有文献进行比较。目的是了解这种疾病的特点和预后，并提供见解，以加强其治疗。方法选择2011 - 2021年在医院（Clínicas da FMUSP）确诊的EMC病例。筛选了14例病例，并对病历进行回顾性分析以收集数据。结果分析涵盖了患者和疾病特征。其中女性占64.3%，平均年龄为71.33岁。腮腺为主要原发部位（92.8%）。关于分期，在III期和IVa期有显著的流行。其中12例接受手术治疗，8例接受辅助治疗。结论：尽管EMC是一种低级别肿瘤，但我们的病例系列与大多数现有文献一致，揭示了一种更高级的表现。这就提出了这样的问题：这种侵袭性是由于晚期诊断还是肿瘤不像想象的那么惰性。证据等级：四级。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Brazilian Journal of Otorhinolaryngology OTORHINOLARYNGOLOGY-

CiteScore

3.00

自引率

0.00%

发文量

205

审稿时长

4-8 weeks

期刊介绍： Brazilian Journal of Otorhinolaryngology publishes original contributions in otolaryngology and the associated areas (cranio-maxillo-facial surgery and phoniatrics). The aim of this journal is the national and international divulgation of the scientific production interesting to the otolaryngology, as well as the discussion, in editorials, of subjects of scientific, academic and professional relevance. The Brazilian Journal of Otorhinolaryngology is born from the Revista Brasileira de Otorrinolaringologia, of which it is the English version, created and indexed by MEDLINE in 2005. It is the official scientific publication of the Brazilian Association of Otolaryngology and Cervicofacial Surgery. Its abbreviated title is Braz J Otorhinolaryngol., which should be used in bibliographies, footnotes and bibliographical references and strips.