Does the diameter of the thoracic inlet influence the formation of retrosternal goiter?

IF 1.7 4区医学 Q2 OTORHINOLARYNGOLOGY

Brazilian Journal of Otorhinolaryngology Pub Date : 2025-05-29 DOI:10.1016/j.bjorl.2025.101597

Leonardo Daniel Manzano Pasquel , Daniel Abreu Rocha , Yasmin Laryssa Moura Guimaraes , Gustavo Fernandes de Alvarenga , Mauricio Kase , Júlia Scomparin Magalhãnes , Regina Lúcia Elia Gomes , Ledo Mazzei Massoni Neto , Renata Lorencetti Mahmoud , Leandro Luongo de Matos , Vergilius José Furtado de Araujo Filho , Claudio Roberto Cernea

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引用次数: 0

Abstract

Objective

Find an association between diameter of the Thoracic Inlet (TI) and RSG to determine whether the TI would function as a natural anatomical barrier to prevent the passage of the goiters to the thoracic cavity.

Methods

A retrospective study was conducted with patients submitted to total thyroidectomy, with goiter greater than 50 cm³, who underwent Computed Tomography (CT) preoperatively to measure the TI volume. The values obtained from each continuous variable of parametric distribution were organized and described as mean and standard deviation. The distributions were defined as non-parametric by the Kolmogorov-Smirnov test. The Mann-Whitney test was used to compare two sample populations.

Results

A total of 173 patients submitted to total thyroidectomy were evaluated, and 54 patients met the inclusion criteria of the study. 85.2% were female, with a mean age of 57-years. The mean diameter of the TI was 5679 mm². 42% of the patients presented some degree of RSG. The distance below the TI ranged from 0.2 to 5 cm.

Conclusion

No significant association was found between diameter of the thoracic inlet and retrosternal goiter, demonstrating that RSG can be present regardless of the TI diameter. Statistically significant association was observed between patients with larger thyroid volume and the likelihood of this tissue to extend to the thoracic cavity.

Level of evidence

Level IV.

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胸椎入口的直径是否影响胸骨后甲状腺肿的形成？

目的探讨胸入口（TI）直径与RSG之间的关系，以确定TI是否能作为天然的解剖屏障，阻止甲状腺肿物进入胸腔。方法回顾性研究行甲状腺全切除术且甲状腺肿大大于50 cm3的患者，术前行CT测量TI体积。从参数分布的每个连续变量得到的值被组织并描述为平均值和标准差。通过Kolmogorov-Smirnov检验将分布定义为非参数分布。曼-惠特尼检验用于比较两个样本群体。结果173例患者接受甲状腺全切除术，54例患者符合纳入标准。85.2%为女性，平均年龄57岁。TI的平均直径为5679 mm2。42%的患者出现不同程度的RSG。TI下方的距离为0.2 ~ 5cm。结论胸廓入口直径与胸廓后甲状腺肿无显著相关性，提示胸廓入口直径与胸廓后甲状腺肿无关。在甲状腺体积较大的患者与该组织延伸到胸腔的可能性之间观察到统计学上显著的关联。证据等级：四级。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Brazilian Journal of Otorhinolaryngology OTORHINOLARYNGOLOGY-

CiteScore

3.00

自引率

0.00%

发文量

205

审稿时长

4-8 weeks

期刊介绍： Brazilian Journal of Otorhinolaryngology publishes original contributions in otolaryngology and the associated areas (cranio-maxillo-facial surgery and phoniatrics). The aim of this journal is the national and international divulgation of the scientific production interesting to the otolaryngology, as well as the discussion, in editorials, of subjects of scientific, academic and professional relevance. The Brazilian Journal of Otorhinolaryngology is born from the Revista Brasileira de Otorrinolaringologia, of which it is the English version, created and indexed by MEDLINE in 2005. It is the official scientific publication of the Brazilian Association of Otolaryngology and Cervicofacial Surgery. Its abbreviated title is Braz J Otorhinolaryngol., which should be used in bibliographies, footnotes and bibliographical references and strips.