Statin use among uninsured individuals in a charity community clinic

IF 3.6 3区 医学 Q2 PHARMACOLOGY & PHARMACY
Zahid Ahmad MD, Christie Tran BS, Michael Pannell BS, Tanvi Ingle MS
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引用次数: 0

Abstract

Background/Synopsis

Limited data exist on lipid-lowering treatment in vulnerable populations, particularly those receiving primary care at charity community clinics. These clinics serve uninsured individuals with little to no access to healthcare providers, including safety-net healthcare systems.

Objective/Purpose

To assess statin therapy among statin-eligible patients at a primary care charity clinic (North Dallas Shared Ministry, NDSM; Dallas, TX).

Methods

We queried the electronic medical records (Athena Health) at NDSM (2016-2024) to extract demographic data, ICD-10 diagnoses, laboratory values, and statin prescriptions for both children and adults. Patients were categorized into four statin benefit groups per the 2018 AHA/ACA cholesterol guidelines. Multivariate logistic regression was performed to identify factors associated with statin prescriptions.

Results

Among 5,097 children (51% female, 89% Hispanic), 28 had lipids checked. One child had LDL-C ≥ 130 mg/dL, potentially qualifying for statin therapy. Among 34,982 adults (median age 41 years, 61% female, 86% Hispanic), 985 had lipids testing and sufficient data to determine if they belong to a statin benefit group. Statin prescription rates by benefit group were: ASCVD (n=43): 70%; diabetes (n=597): 58%; LDL-C ≥ 190 mg/dL (n=39): 87%; ASCVD risk ≥ 7.5%: 41%. Overall, 54% of statin-eligible patients were prescribed statins. In multivariate analysis, factors associated with statin prescriptions included age (OR 2.6, 95% CI 1.8, 3.6), diabetes diagnosis (OR 6.0, 95% CI 3.2, 11.5), total cholesterol (OR 2.5, 95% CI 2.1, 3.0), and HDL-C (OR 0.7, 95% CI 0.5, 0.7), (p < 0.0001, C-index 0.889).

Conclusions

Among uninsured patients in a primary care, charity community clinic, statin prescription rates were slightly higher than those reported in insured populations (∼50%), with similar predictors of statin prescriptions (e.g., age, diabetes diagnosis, lipid levels). However, lipid screening was infrequent – only 3% of adult patients had lipids checked – suggesting most statin-eligible patients likely remain unidentified. These findings highlight a critical gap: the need to improve lipid screening in uninsured populations to ensure at-risk individuals are identified and treated appropriately. In addition, future analyses should assess not only statin prescription rates but also whether patients receive appropriate statin intensity and non-statin therapies like ezetimibe and PCSK9 inhibitors.
他汀类药物在慈善社区诊所无保险个人中的使用
背景/概要关于弱势人群降脂治疗的数据有限,特别是那些在慈善社区诊所接受初级保健的人群。这些诊所为没有保险的个人提供服务,他们几乎没有机会获得医疗保健服务,包括安全网医疗保健系统。目的/目的评估他汀类药物在初级保健慈善诊所(North Dallas Shared Ministry, NDSM;达拉斯,TX)。方法:我们查询NDSM(2016-2024)的电子病历(Athena Health),提取儿童和成人的人口统计数据、ICD-10诊断、实验室值和他汀类药物处方。根据2018年AHA/ACA胆固醇指南,患者被分为四个他汀类药物受益组。进行多因素logistic回归以确定与他汀类药物处方相关的因素。结果在5097名儿童中(51%为女性,89%为西班牙裔),28名儿童进行了血脂检查。一名儿童LDL-C≥130 mg/dL,可能适合他汀类药物治疗。在34,982名成年人(中位年龄41岁,61%为女性,86%为西班牙裔)中,985人进行了血脂检测,并获得了足够的数据来确定他们是否属于他汀类药物受益组。获益组他汀类药物处方率分别为:ASCVD (n=43): 70%;糖尿病(n=597): 58%;LDL-C≥190 mg/dL (n=39): 87%;ASCVD风险≥7.5%:41%。总体而言,54%符合他汀类药物条件的患者服用了他汀类药物。在多变量分析中,与他汀类药物处方相关的因素包括年龄(OR 2.6, 95% CI 1.8, 3.6)、糖尿病诊断(OR 6.0, 95% CI 3.2, 11.5)、总胆固醇(OR 2.5, 95% CI 2.1, 3.0)和HDL-C (OR 0.7, 95% CI 0.5, 0.7), (p <;0.0001, c指数0.889)。结论:在初级保健、慈善社区诊所的未参保患者中,他汀类药物的处方率略高于参保人群(约50%),他汀类药物处方的预测因子相似(如年龄、糖尿病诊断、血脂水平)。然而,脂质筛查很少,只有3%的成年患者进行了脂质检查,这表明大多数符合他汀类药物条件的患者可能仍未确定。这些发现突出了一个关键的差距:需要改善无保险人群的脂质筛查,以确保有风险的个体得到适当的识别和治疗。此外,未来的分析不仅应该评估他汀类药物的处方率,还应该评估患者是否接受了适当的他汀类药物强度和非他汀类药物治疗,如依zetimibe和PCSK9抑制剂。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
CiteScore
7.00
自引率
6.80%
发文量
209
审稿时长
49 days
期刊介绍: Because the scope of clinical lipidology is broad, the topics addressed by the Journal are equally diverse. Typical articles explore lipidology as it is practiced in the treatment setting, recent developments in pharmacological research, reports of treatment and trials, case studies, the impact of lifestyle modification, and similar academic material of interest to the practitioner. Sections of Journal of clinical lipidology will address pioneering studies and the clinicians who conduct them, case studies, ethical standards and conduct, professional guidance such as ATP and NCEP, editorial commentary, letters from readers, National Lipid Association (NLA) news and upcoming event information, as well as abstracts from the NLA annual scientific sessions and the scientific forums held by its chapters, when appropriate.
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