Accelerating evidence generation to implementation in cardiometabolic health: Establishment of the LATTICE Consortium

IF 3.6 3区医学 Q2 PHARMACOLOGY & PHARMACY

Journal of clinical lipidology Pub Date : 2025-05-01 DOI:10.1016/j.jacl.2025.04.008

Ankeet Bhatt MD, Leandro Boer MD, Gemme Campbell-Salome PhD, Erica Davis, Nihar Desai MD, Jyothis George MD, Ty Gluckman MD, Lisa Head PharmD, Francoise Marvel MD, Marc Penn MD, Eric Peterson MD, Nishant Shah MD, Katherine Wilemon, Bethany Kalich PharmD, Seth Martin MD, Laney Jones PharmD

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引用次数: 0

Abstract

Background/Synopsis

Recent scientific advancements have led to the development of innovative therapies to reduce the risk of cardiometabolic events, offering new hope to address the world's leading cause of mortality. However, the time from evidence generation in the research-setting to implementation in the care-setting is elongated, has resulted in a high rate of cardiovascular and metabolic consequences for patients, clinicians, and health systems in the United States.

Objective/Purpose

Improved collaboration among patients, clinicians, health systems, payers, patient advocacy, and life science companies to translate evidence-based advancements into clinical practice is key to closing this health care gap.

Methods

Utilizing implementation science theories, methods, and frameworks can improve translation of evidence-based practices to improve cardiometabolic care. To close the gaps in cardiometabolic care, we will evaluate implementation tools, methodologies, and strategies. We will then measure both implementation and health outcomes.

Results

We describe the establishment of the LATTICE consortium, Leading Awareness to Action through Implementation of Cardiometabolic Efforts. LATTICE is a first-of-its-kind community dedicated to addressing cardiometabolic patient needs through implementation efforts (Figure). The LATTICE consortium helps unite partners contributing to the overall mission of improving cardiometabolic health by creating an inclusive platform for sharing evidence-based tools, methodologies, and strategies and collaborating to improve the effectiveness of cardiometabolic patient care at scale.

Conclusions

Success of LATTICE consortium will be measured by reducing time from evidence generation to implementation, improved awareness, and downstream implementation by individuals of successful, scalable, and sustainable care strategies that close cardiometabolic care gaps in meaningful ways.

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加速心脏代谢健康的证据生成和实施：LATTICE联盟的建立

背景/摘要最近的科学进步导致了创新疗法的发展，以降低心脏代谢事件的风险，为解决世界上主要的死亡原因提供了新的希望。然而，从研究环境中的证据生成到在护理环境中实施的时间被延长，导致美国患者、临床医生和卫生系统的心血管和代谢后果发生率很高。改善患者、临床医生、卫生系统、支付方、患者倡导和生命科学公司之间的合作，将循证进展转化为临床实践，是缩小这一卫生保健差距的关键。方法应用实施科学的理论、方法和框架可以提高循证实践的转化，以改善心脏代谢护理。为了缩小心脏代谢护理的差距，我们将评估实施工具、方法和策略。然后，我们将衡量实施和健康结果。结果我们描述了LATTICE联盟的建立，通过实施心脏代谢努力将意识引导到行动。LATTICE是首个致力于通过实施努力解决心脏代谢患者需求的社区（图）。LATTICE联盟通过创建一个包容性的平台来共享基于证据的工具、方法和策略，并通过合作来大规模提高心脏代谢患者护理的有效性，帮助联合合作伙伴，共同致力于改善心脏代谢健康的总体使命。LATTICE联盟的成功将通过减少从证据产生到实施的时间、提高意识和个体对成功、可扩展和可持续的护理策略的下游实施来衡量，这些策略以有意义的方式缩小了心脏代谢护理差距。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Journal of clinical lipidology 医学-药学

CiteScore

7.00

自引率

6.80%

发文量

209

审稿时长

49 days

期刊介绍： Because the scope of clinical lipidology is broad, the topics addressed by the Journal are equally diverse. Typical articles explore lipidology as it is practiced in the treatment setting, recent developments in pharmacological research, reports of treatment and trials, case studies, the impact of lifestyle modification, and similar academic material of interest to the practitioner. Sections of Journal of clinical lipidology will address pioneering studies and the clinicians who conduct them, case studies, ethical standards and conduct, professional guidance such as ATP and NCEP, editorial commentary, letters from readers, National Lipid Association (NLA) news and upcoming event information, as well as abstracts from the NLA annual scientific sessions and the scientific forums held by its chapters, when appropriate.