Strategies for combating FIPV infection: antiviral agents and vaccines

IF 2.2 3区农林科学 Q1 VETERINARY SCIENCES

Research in veterinary science Pub Date : 2025-05-27 DOI:10.1016/j.rvsc.2025.105709

Fan Gao, Guilan Wen

引用次数: 0

Abstract

Feline infectious peritonitis virus (FIPV) is a deadly virus that causes feline infectious peritonitis (FIP) in cats. FIP is a biotype of feline coronavirus (FCoV). Currently, the prevention and treatment of FIPV is challenged by the absence of adequate clinical treatment drugs and vaccines that offer strong immune protection complicated. In this review, we analyse and explain how small-molecule inhibitors function to protect against viral infections. Additionally, we highlight the challenges and future possibilities in developing FIPV vaccines, which are crucial for enhancing FIPV treatment and creating viable vaccine solution strategies.

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抗击FIPV感染的战略：抗病毒药物和疫苗

猫传染性腹膜炎病毒（FIPV）是一种致猫传染性腹膜炎（FIP）的致命病毒。FIP是猫冠状病毒（FCoV）的一种生物型。目前，由于缺乏足够的临床治疗药物和具有较强免疫保护作用的疫苗，对FIPV的预防和治疗提出了挑战。在这篇综述中，我们分析和解释了小分子抑制剂是如何保护人体免受病毒感染的。此外，我们强调了开发FIPV疫苗的挑战和未来的可能性，这对于加强FIPV治疗和创造可行的疫苗解决策略至关重要。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Research in veterinary science 农林科学-兽医学

CiteScore

4.40

自引率

4.20%

发文量

312

审稿时长

75 days

期刊介绍： Research in Veterinary Science is an International multi-disciplinary journal publishing original articles, reviews and short communications of a high scientific and ethical standard in all aspects of veterinary and biomedical research. The primary aim of the journal is to inform veterinary and biomedical scientists of significant advances in veterinary and related research through prompt publication and dissemination. Secondly, the journal aims to provide a general multi-disciplinary forum for discussion and debate of news and issues concerning veterinary science. Thirdly, to promote the dissemination of knowledge to a broader range of professions, globally. High quality papers on all species of animals are considered, particularly those considered to be of high scientific importance and originality, and with interdisciplinary interest. The journal encourages papers providing results that have clear implications for understanding disease pathogenesis and for the development of control measures or treatments, as well as those dealing with a comparative biomedical approach, which represents a substantial improvement to animal and human health. Studies without a robust scientific hypothesis or that are preliminary, or of weak originality, as well as negative results, are not appropriate for the journal. Furthermore, observational approaches, case studies or field reports lacking an advancement in general knowledge do not fall within the scope of the journal.