Protocolo de profilaxis y manejo de las infecciones con los tratamientos biológicos inmunomoduladores y los inhibidores de JAK

Abstract

This protocol addresses recommendations on infection prophylaxis and management for patients with inflammatory autoimmune diseases in treatment with biologic drugs and JAK inhibitors. The importance of an annual evaluation of vaccination status is notable, prioritizing administration in quiescent disease stages and before initiating immunosuppressive treatments. It includes considerations for non-live vaccines that are safe in immunocompromised patients and specific guidelines for live vaccines under controlled conditions. In addition, personalized strategies are suggested according to individual factors such as treatment, risk of infection, and local epidemiology.