Synergistic Cobaloxime Catalysis for Photo-Dehydrogenative Transformations

IF 11.3 1区化学 Q1 CHEMISTRY, PHYSICAL

ACS Catalysis Pub Date : 2025-05-29 DOI:10.1021/acscatal.5c00343

Aindrila Mandal, Matthew Lim, Lili Zhang, Kuo-Wei Huang, Shashikant U. Dighe

引用次数: 0

Abstract

Cobaloxime catalysis has emerged as a powerful tool for promoting dehydrogenation reactions and enabling small-molecule functionalization under environmentally benign conditions. These transformations are essential for constructing sp²-hybridized C–C bonds, crucial for synthesizing high-value alkenes, arenes, and heterocycles with applications in pharmaceuticals, agrochemicals and advanced materials. The integration of cobaloxime with photoredox catalysis further enhances reaction efficiency, offering improved selectivity and yields under milder conditions. This review highlights recent advancements in the application of cobaloxime within metallaphotoredox catalysis, with a focus on its effectiveness in dehydrogenation processes that drive the formation of sp²-hybridized C–C bonds via hydrogen atom transfer (HAT) and related pathways.

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协同钴肟催化光脱氢转化

钴肟催化已成为促进脱氢反应和在环境无害条件下实现小分子功能化的有力工具。这些转化对于构建sp2杂化C-C键至关重要，对于合成高价值的烯烃、芳烃和杂环具有重要意义，在制药、农用化学品和先进材料中具有重要应用。钴胺肟与光氧化还原催化的结合进一步提高了反应效率，在更温和的条件下提供了更好的选择性和收率。本文综述了钴肟在金属光氧化还原催化中应用的最新进展，重点介绍了其在脱氢过程中的有效性，脱氢过程通过氢原子转移（HAT）和相关途径驱动sp2杂化C-C键的形成。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

ACS Catalysis CHEMISTRY, PHYSICAL-

CiteScore

20.80

自引率

6.20%

发文量

1253

审稿时长

1.5 months

期刊介绍： ACS Catalysis is an esteemed journal that publishes original research in the fields of heterogeneous catalysis, molecular catalysis, and biocatalysis. It offers broad coverage across diverse areas such as life sciences, organometallics and synthesis, photochemistry and electrochemistry, drug discovery and synthesis, materials science, environmental protection, polymer discovery and synthesis, and energy and fuels. The scope of the journal is to showcase innovative work in various aspects of catalysis. This includes new reactions and novel synthetic approaches utilizing known catalysts, the discovery or modification of new catalysts, elucidation of catalytic mechanisms through cutting-edge investigations, practical enhancements of existing processes, as well as conceptual advances in the field. Contributions to ACS Catalysis can encompass both experimental and theoretical research focused on catalytic molecules, macromolecules, and materials that exhibit catalytic turnover.