An asymmetric transformation of carbenium ions

IF 42.8 1区化学 Q1 CHEMISTRY, PHYSICAL

Nature Catalysis Pub Date : 2025-05-28 DOI:10.1038/s41929-025-01330-9

引用次数: 0

Abstract

The enantiocontrolled conversion of carbenium ions presents a challenge owing to their instability and high reactivity. Through the combination of a chiral organocatalyst and photocatalyst, the intramolecular enantioselective and enantioconvergent amidation of C(sp3)–H bonds is now demonstrated, affording chiral oxazolidinone products via a transient carbenium ion complex.

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碳离子的不对称转变

由于碳离子的不稳定性和高反应性，其对映控制转化是一个挑战。通过手性有机催化剂和光催化剂的结合，现已证明了C(sp3) -H键的分子内对映选择性和对映收敛性酰胺化，通过瞬态碳离子络合物提供手性恶唑烷酮产品。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Nature Catalysis Chemical Engineering-Bioengineering

CiteScore

52.10

自引率

1.10%

发文量

140

期刊介绍： Nature Catalysis serves as a platform for researchers across chemistry and related fields, focusing on homogeneous catalysis, heterogeneous catalysis, and biocatalysts, encompassing both fundamental and applied studies. With a particular emphasis on advancing sustainable industries and processes, the journal provides comprehensive coverage of catalysis research, appealing to scientists, engineers, and researchers in academia and industry. Maintaining the high standards of the Nature brand, Nature Catalysis boasts a dedicated team of professional editors, rigorous peer-review processes, and swift publication times, ensuring editorial independence and quality. The journal publishes work spanning heterogeneous catalysis, homogeneous catalysis, and biocatalysis, covering areas such as catalytic synthesis, mechanisms, characterization, computational studies, nanoparticle catalysis, electrocatalysis, photocatalysis, environmental catalysis, asymmetric catalysis, and various forms of organocatalysis.