Characterization of an Emerging Recombinant Duck Circovirus in Northern Vietnam, 2023-2024.

IF 3.8 3区医学 Q2 VIROLOGY

Viruses-Basel Pub Date : 2025-05-20 DOI:10.3390/v17050732

Hieu Van Dong, Dai Quang Trinh, Giang Huong Thi Tran, Thanh Thi Vu, Thinh Hung Ba Nguyen, Amonpun Rattanasrisomporn, Dao Anh Tran Bui, Jatuporn Rattanasrisomporn

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Abstract

This study aimed to characterize the duck circovirus circulating in Northern Vietnam based on complete genome sequences. Between 2023 and 2025, 45 pooled tissue samples were collected from nine duck flocks in several provinces in Northern Vietnam. Of the 45 samples tested, 16 (35.56%) were positive for the DuCV genome, as determined using conventional polymerase chain reaction. Nine representative strains were selected for viral genome sequencing. The results indicated that the complete Vietnamese DuCV genomes were from 1992 to 1995 bp in length, and the degree of nucleotide identity shared among them ranged from 96.88% to 99.84%. Phylogenetic analysis of the complete genomes showed that the nine Vietnamese DuCV strains belonged to genotype I, subgenotypes Ia (two strains), Ib (four strains), and Ic (three strains). These viral strains were genetically related to viruses reported in China from 2019 to 2023. Recombination events occurred on the Cap gene sequences of three Vietnamese DuCV strains (Vietnam/VNUA-102/2023, Vietnam/VNUA-225/2023, and Vietnam/VNUA-318/2024). One positive selection was detected on the Rep protein sequence.

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2023-2024年越南北部新出现的重组鸭圆环病毒的特性

本研究旨在对越南北部流行的鸭圆环病毒进行全基因组测序。在2023年至2025年期间，从越南北部几个省份的9个鸭群中收集了45个汇总组织样本。在检测的45份样本中，16份（35.56%）采用常规聚合酶链反应检测DuCV基因组阳性。选取9株代表性菌株进行病毒基因组测序。结果表明，越南DuCV全基因组长度在1992 ~ 1995 bp之间，核苷酸同源度在96.88% ~ 99.84%之间。全基因组系统发育分析表明，9株越南DuCV菌株分别属于I基因型、Ia亚基因型（2株）、Ib亚基因型（4株）和Ic亚基因型（3株）。这些病毒株与2019年至2023年在中国报告的病毒具有遗传相关性。3株越南DuCV株（Vietnam/VNUA-102/2023、Vietnam/VNUA-225/2023和Vietnam/VNUA-318/2024）的Cap基因序列均发生重组。在Rep蛋白序列上检测到一个阳性选择。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Viruses-Basel VIROLOGY-

CiteScore

7.30

自引率

12.80%

发文量

2445

审稿时长

1 months

期刊介绍： Viruses (ISSN 1999-4915) is an open access journal which provides an advanced forum for studies of viruses. It publishes reviews, regular research papers, communications, conference reports and short notes. Our aim is to encourage scientists to publish their experimental and theoretical results in as much detail as possible. There is no restriction on the length of the papers. The full experimental details must be provided so that the results can be reproduced. We also encourage the publication of timely reviews and commentaries on topics of interest to the virology community and feature highlights from the virology literature in the ''News and Views'' section. Electronic files or software regarding the full details of the calculation and experimental procedure, if unable to be published in a normal way, can be deposited as supplementary material.