Anorexia nervosa-an update.

IF 0.9 4区医学 Q4 CLINICAL NEUROLOGY

Nervenarzt Pub Date : 2025-05-28 DOI:10.1007/s00115-025-01820-y

Ulrich Voderholzer, Silke Naab, Ulrich Cuntz, Sandra Schlegl

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Abstract

Anorexia nervosa (AN) is a severe psychiatric disorder with the highest mortality rate among eating disorders. It predominantly affects adolescents and young adults, with a significant increase in prevalence among adolescents observed since the coronavirus disease 2019 (COVID-19) pandemic. It is frequently associated with other psychiatric disorders, such as depression, anxiety and obsessive-compulsive disorders as well as numerous physical complications. An early diagnosis and treatment are associated with better outcomes. The treatment of choice for AN includes cognitive behavioral therapy and family-based therapy for children and adolescents. Innovative treatment approaches, such as home treatment and technology-based interventions, have shown promising preliminary results. With the exception of moderate evidence supporting the use of olanzapine regarding weight gain, there is currently no evidence for the efficacy of psychopharmacotherapy in AN. Future research should focus on prevention, early detection and intervention, relapse prevention, personalized treatment approaches, management of comorbid disorders, long-term studies and the influence of psychosocial factors.

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神经性厌食症——最新消息。

神经性厌食症是一种严重的精神疾病，在饮食失调症中死亡率最高。它主要影响青少年和年轻人，自2019年冠状病毒病（COVID-19）大流行以来，青少年的患病率显著增加。它经常与其他精神疾病有关，如抑郁、焦虑和强迫症以及许多身体并发症。早期诊断和治疗与更好的结果相关。AN的治疗选择包括儿童和青少年的认知行为疗法和以家庭为基础的疗法。创新的治疗方法，如家庭治疗和基于技术的干预，已经显示出有希望的初步结果。除了中度证据支持使用奥氮平治疗体重增加外，目前没有证据表明精神药物治疗对AN的疗效。未来的研究应侧重于预防、早期发现和干预、复发预防、个性化治疗方法、合并症的管理、长期研究和社会心理因素的影响。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Nervenarzt 医学-精神病学

CiteScore

2.50

自引率

18.20%

发文量

169

审稿时长

4-8 weeks

期刊介绍： Der Nervenarzt is an internationally recognized journal addressing neurologists and psychiatrists working in clinical or practical environments. Essential findings and current information from neurology, psychiatry as well as neuropathology, neurosurgery up to psychotherapy are presented. Review articles provide an overview on selected topics and offer the reader a summary of current findings from all fields of neurology and psychiatry. Freely submitted original papers allow the presentation of important clinical studies and serve the scientific exchange. Review articles under the rubric ''Continuing Medical Education'' present verified results of scientific research and their integration into daily practice.