Options for Regenerative Treatment with Bone Grafts in Children with Anterior Lip/Palate Cleft-A Review.

IF 2 4区医学 Q2 PEDIATRICS

Children-Basel Pub Date : 2025-04-26 DOI:10.3390/children12050559

Anna Miguel-Escribano, Cosimo Galletti, Juan de Quixano-Bardaji, Francisco Real-Voltas, Luca Fiorillo, Maria Cuevas-Nunez, Fulvia Galletti, Javier Flores-Fraile

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引用次数: 0

Abstract

Anterior lip/palate cleft is a congenital deformity affecting the upper lip and palate, posing significant challenges in both aesthetic and functional aspects for children. Effective management of this condition is crucial for improving quality of life and ensuring normal development. This review aims to highlight the regenerative treatment options available for children with anterior lip/palate cleft, focusing on the use of bone grafts and other advanced dental procedures. A review of the current literature and clinical practices was conducted to identify and evaluate the most effective treatment options. Emphasis was placed on regenerative techniques, particularly the use of bone grafts. Advancements in regenerative dentistry offer promising outcomes for children with anterior lip/palate cleft. Bone grafts, combined with innovative techniques such as growth factors, stem cell therapy, and distraction osteogenesis, provide effective solutions for restoring function and aesthetics. A multidisciplinary approach is essential to ensure comprehensive care and optimal results for these patients.

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儿童前唇/腭裂骨移植再生治疗的选择综述

前唇颚裂是一种影响上唇和上颚的先天性畸形，对儿童的审美和功能都提出了重大挑战。有效的治疗对于提高生活质量和确保正常发育至关重要。这篇综述的目的是强调再生治疗选择可用于前唇/腭裂的儿童，重点是使用骨移植物和其他先进的牙科手术。我们回顾了目前的文献和临床实践，以确定和评估最有效的治疗方案。重点放在再生技术上，特别是骨移植的使用。再生牙科的进步为前唇/腭裂儿童提供了有希望的结果。骨移植结合生长因子、干细胞治疗和牵张成骨等创新技术，为恢复功能和美观提供了有效的解决方案。多学科的方法是必不可少的，以确保全面的护理和最佳的结果，为这些患者。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Children-Basel PEDIATRICS-

CiteScore

2.70

自引率

16.70%

发文量

1735

审稿时长

6 weeks

期刊介绍： Children is an international, open access journal dedicated to a streamlined, yet scientifically rigorous, dissemination of peer-reviewed science related to childhood health and disease in developed and developing countries. The publication focuses on sharing clinical, epidemiological and translational science relevant to children’s health. Moreover, the primary goals of the publication are to highlight under‑represented pediatric disciplines, to emphasize interdisciplinary research and to disseminate advances in knowledge in global child health. In addition to original research, the journal publishes expert editorials and commentaries, clinical case reports, and insightful communications reflecting the latest developments in pediatric medicine. By publishing meritorious articles as soon as the editorial review process is completed, rather than at predefined intervals, Children also permits rapid open access sharing of new information, allowing us to reach the broadest audience in the most expedient fashion.