Feasibility of Endoscopic Ultrasound-Guided Tissue Acquisition for < 20-mm Upper Gastrointestinal Subepithelial Lesions.

IF 3.7 3区医学 Q2 GASTROENTEROLOGY & HEPATOLOGY

Journal of Gastroenterology and Hepatology Pub Date : 2025-05-28 DOI:10.1111/jgh.17029

Masafumi Watanabe, Kosuke Okuwaki, Tomohisa Iwai, Mitsuhiro Kida, Hiroshi Imaizumi, Kai Adachi, Akihiro Tamaki, Junro Ishizaki, Taro Hanaoka, Chika Kusano

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引用次数: 0

Abstract

Background: There are few reports on the usefulness of endoscopic ultrasound-guided tissue acquisition (EUS-TA) for upper gastrointestinal subepithelial lesions (SELs) < 20 mm with on-site stereomicroscopic assessment.

Aim: This study is aimed at investigating the usefulness of EUS-TA combined with on-site stereomicroscopic assessment using fine-needle biopsy (FNB) for SELs < 20 mm.

Methods: Participants (n = 133) underwent EUS-TA combined with on-site stereomicroscopic assessment using a 22-gauge FNB needle for upper gastrointestinal SELs between January 2018 and January 2022. We conducted a comparative study of diagnostic results after dividing the participants into two groups on the basis of lesion size: < 20 and ≥ 20 mm.

Results: There were 42 cases in the < 20-mm group and 91 cases in the ≥ 20-mm group. The diagnostic yield of EUS-TA in all cases was 97.7%, with values of 97.6% in the < 20-mm group and 97.8% in the ≥ 20-mm group and no significant difference between the groups. A total of 298 passes were made. The tissue sampling rate was 99.0%, and specimens with stereomicroscopically visible white cores (SVWCs) ≥ 4 mm were sampled at a rate of 87.2%. There was no significant difference in the sampling rate of specimens with SVWCs ≥ 4 mm between the groups. The diagnostic sensitivity in specimens with SVWC ≥ 4 mm was 98.5% (256/260 passes). Multivariate analysis showed that this factor significantly contributed to diagnosis (odds ratio 24.396, 95% confidence interval: 1.6596-4.7292, p < 0.001).

Conclusions: EUS-TA using a FNB needle combined with on-site stereomicroscopic assessment is a useful diagnostic method for < 20-mm SELs.

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超声内镜引导下获取< 20毫米上消化道上皮下病变组织的可行性。

背景：关于超声内镜引导下组织采集（EUS-TA）对上消化道上皮下病变（SELs）的有效性报道很少。目的：本研究旨在探讨超声内镜引导下组织采集（EUS-TA）联合细针活检（FNB）现场立体显微镜评估SELs的有效性。在2018年1月至2022年1月期间，参与者（n = 133）使用22号FNB针进行EUS-TA结合现场立体显微镜评估上消化道SELs。我们根据病变大小将参与者分为两组，对诊断结果进行对比研究：结果：本组共42例。结论：采用FNB针EUS-TA结合现场立体显微镜评估是一种有用的诊断方法

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Journal of Gastroenterology and Hepatology 医学-胃肠肝病学

CiteScore

7.90

自引率

2.40%

发文量

326

审稿时长

2.3 months

期刊介绍： Journal of Gastroenterology and Hepatology is produced 12 times per year and publishes peer-reviewed original papers, reviews and editorials concerned with clinical practice and research in the fields of hepatology, gastroenterology and endoscopy. Papers cover the medical, radiological, pathological, biochemical, physiological and historical aspects of the subject areas. All submitted papers are reviewed by at least two referees expert in the field of the submitted paper.