Biomechanical Analysis of Rheumatoid Arthritis of the Hand and the Design of Orthotics: A Finite Element Study.

IF 3.8 3区 医学 Q2 ENGINEERING, BIOMEDICAL
Guiyuan Li, Jie Yang, Pengfei Feng, Xiaona Li, Weiyi Chen
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Abstract

Hand orthoses are often recommended as a rehabilitation measure for patients with rheumatoid arthritis (RA). However, existing research on the efficacy of hand orthoses has predominantly focused on 3D-printed devices and post-intervention clinical functional assessments, which tend to be subjective. There is a notable lack of biomechanical studies evaluating the effects of wearing orthoses. Therefore, in this study, the finite element method was used to analyze the biomechanical properties of an RA hand. A hand orthosis was designed based on the principle of three-point force, and a composite model of the RA hand and orthosis was constructed to verify its effectiveness. The results showed that the peak stress and displacement of the RA hand were 3.22-183.21% and 28.81-124.23% higher than those of the normal hand. Compared with the RA hand under direct force, the peak stress of the RA hand after wearing orthosis was generally reduced by 3.05-55.60%, and the peak displacement was generally reduced by 20.35-71.43%, verifying the effectiveness of the orthosis. Additionally, variations in the magnitude of three-point forces influenced the orthopedic effects. This study proves the effectiveness of hand orthosis and provides some theoretical data for subsequent research and treatment of rheumatoid arthritis.

手部类风湿关节炎的生物力学分析及矫形器的设计:一项有限元研究。
手部矫形器经常被推荐作为类风湿性关节炎(RA)患者的康复措施。然而,现有关于手部矫形器疗效的研究主要集中在3d打印设备和干预后的临床功能评估上,这些研究往往是主观的。目前还缺乏对佩戴矫形器效果的生物力学研究。因此,本研究采用有限元方法分析RA手的生物力学特性。基于三点力原理设计了一种手部矫形器,并建立了RA手部与矫形器的复合模型,验证了其有效性。结果表明,RA手的峰值应力和位移分别比正常手高3.22 ~ 183.21%和28.81 ~ 124.23%。与直接受力的RA手相比,佩戴矫形器后RA手的峰值应力普遍降低3.05-55.60%,峰值位移普遍降低20.35-71.43%,验证了矫形器的有效性。此外,三点力大小的变化影响了矫形效果。本研究证明了手部矫形器的有效性,为类风湿关节炎的后续研究和治疗提供了一定的理论数据。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
Bioengineering
Bioengineering Chemical Engineering-Bioengineering
CiteScore
4.00
自引率
8.70%
发文量
661
期刊介绍: Aims Bioengineering (ISSN 2306-5354) provides an advanced forum for the science and technology of bioengineering. It publishes original research papers, comprehensive reviews, communications and case reports. Our aim is to encourage scientists to publish their experimental and theoretical results in as much detail as possible. All aspects of bioengineering are welcomed from theoretical concepts to education and applications. There is no restriction on the length of the papers. The full experimental details must be provided so that the results can be reproduced. There are, in addition, four key features of this Journal: ● We are introducing a new concept in scientific and technical publications “The Translational Case Report in Bioengineering”. It is a descriptive explanatory analysis of a transformative or translational event. Understanding that the goal of bioengineering scholarship is to advance towards a transformative or clinical solution to an identified transformative/clinical need, the translational case report is used to explore causation in order to find underlying principles that may guide other similar transformative/translational undertakings. ● Manuscripts regarding research proposals and research ideas will be particularly welcomed. ● Electronic files and software regarding the full details of the calculation and experimental procedure, if unable to be published in a normal way, can be deposited as supplementary material. ● We also accept manuscripts communicating to a broader audience with regard to research projects financed with public funds. Scope ● Bionics and biological cybernetics: implantology; bio–abio interfaces ● Bioelectronics: wearable electronics; implantable electronics; “more than Moore” electronics; bioelectronics devices ● Bioprocess and biosystems engineering and applications: bioprocess design; biocatalysis; bioseparation and bioreactors; bioinformatics; bioenergy; etc. ● Biomolecular, cellular and tissue engineering and applications: tissue engineering; chromosome engineering; embryo engineering; cellular, molecular and synthetic biology; metabolic engineering; bio-nanotechnology; micro/nano technologies; genetic engineering; transgenic technology ● Biomedical engineering and applications: biomechatronics; biomedical electronics; biomechanics; biomaterials; biomimetics; biomedical diagnostics; biomedical therapy; biomedical devices; sensors and circuits; biomedical imaging and medical information systems; implants and regenerative medicine; neurotechnology; clinical engineering; rehabilitation engineering ● Biochemical engineering and applications: metabolic pathway engineering; modeling and simulation ● Translational bioengineering
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