{"title":"Digitally Guided Precision Fat Grafting for Progressive Hemifacial Atrophy.","authors":"Guojie Chen, Qiang Fu, Xiao Xu, Lili Xu, Peixuan Zhang, Tianran Li, Minliang Chen","doi":"10.1007/s00266-025-04923-8","DOIUrl":null,"url":null,"abstract":"<p><strong>Background: </strong>Autologous fat grafting (AFG) is widely used to treat progressive hemifacial atrophy (PHA), but accurate measurement of tissue defects in PHA patients remains a challenge due to varied facial defects and complex anatomy.</p><p><strong>Methods: </strong>This retrospective study monitored patients undergoing AFG over 12-16 months. Using 3D computed tomography (CT), the midsagittal plane of the face was scanned, mirror-image analysis (MIA) was carried out, and soft tissue volume loss was predicted across facial regions. The patients were evaluated at four intervals (preoperatively and at 3, 6, and 12 months postoperatively) by calculating the asymmetry index (AI), asymmetry rate (AR), preoperative soft tissue volume deficiency (Preop STVD), volume deficiency rate (VDR), and percentage volume maintenance (PVM). Patient characteristics, satisfaction, and outcomes were also analyzed.</p><p><strong>Results: </strong>Fifteen patients (mean age 22) underwent an average of 1.9 AFG surgeries. Preoperative soft tissue defect volume was measured at 101.96 ± 82.52 cm<sup>3</sup>, with an average fat injection volume of 93.38 ± 73.71 cm<sup>3</sup>. Tissue defect rates ranged from 1.43 to 10.16% (mean 4.42 ± 3.47%), and volume maintenance varied from 35.60 to 79.16% (average 56.64 ± 13.48%). Postoperatively, defect rates ranged from 0.78 to 4.86% (mean 2.11 ± 1.66%), with volume maintenance between 52.36 and 71.74% (average 63.50 ± 8.09%). Significant improvements in facial symmetry and patient satisfaction were noted, with no complications reported.</p><p><strong>Conclusion: </strong>Digitally guided precision fat grafting is a promising method for predicting soft tissue loss and improving facial symmetry in patients with progressive hemifacial atrophy.</p><p><strong>Level of evidence iv: </strong>This journal requires that authors assign a level of evidence to each article. For a full description of these Evidence-Based Medicine ratings, please refer to the Table of Contents or the online Instructions to Authors www.springer.com/00266 .</p>","PeriodicalId":7609,"journal":{"name":"Aesthetic Plastic Surgery","volume":" ","pages":""},"PeriodicalIF":2.0000,"publicationDate":"2025-05-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Aesthetic Plastic Surgery","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1007/s00266-025-04923-8","RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"SURGERY","Score":null,"Total":0}
引用次数: 0
Abstract
Background: Autologous fat grafting (AFG) is widely used to treat progressive hemifacial atrophy (PHA), but accurate measurement of tissue defects in PHA patients remains a challenge due to varied facial defects and complex anatomy.
Methods: This retrospective study monitored patients undergoing AFG over 12-16 months. Using 3D computed tomography (CT), the midsagittal plane of the face was scanned, mirror-image analysis (MIA) was carried out, and soft tissue volume loss was predicted across facial regions. The patients were evaluated at four intervals (preoperatively and at 3, 6, and 12 months postoperatively) by calculating the asymmetry index (AI), asymmetry rate (AR), preoperative soft tissue volume deficiency (Preop STVD), volume deficiency rate (VDR), and percentage volume maintenance (PVM). Patient characteristics, satisfaction, and outcomes were also analyzed.
Results: Fifteen patients (mean age 22) underwent an average of 1.9 AFG surgeries. Preoperative soft tissue defect volume was measured at 101.96 ± 82.52 cm3, with an average fat injection volume of 93.38 ± 73.71 cm3. Tissue defect rates ranged from 1.43 to 10.16% (mean 4.42 ± 3.47%), and volume maintenance varied from 35.60 to 79.16% (average 56.64 ± 13.48%). Postoperatively, defect rates ranged from 0.78 to 4.86% (mean 2.11 ± 1.66%), with volume maintenance between 52.36 and 71.74% (average 63.50 ± 8.09%). Significant improvements in facial symmetry and patient satisfaction were noted, with no complications reported.
Conclusion: Digitally guided precision fat grafting is a promising method for predicting soft tissue loss and improving facial symmetry in patients with progressive hemifacial atrophy.
Level of evidence iv: This journal requires that authors assign a level of evidence to each article. For a full description of these Evidence-Based Medicine ratings, please refer to the Table of Contents or the online Instructions to Authors www.springer.com/00266 .
期刊介绍:
Aesthetic Plastic Surgery is a publication of the International Society of Aesthetic Plastic Surgery and the official journal of the European Association of Societies of Aesthetic Plastic Surgery (EASAPS), Società Italiana di Chirurgia Plastica Ricostruttiva ed Estetica (SICPRE), Vereinigung der Deutschen Aesthetisch Plastischen Chirurgen (VDAPC), the Romanian Aesthetic Surgery Society (RASS), Asociación Española de Cirugía Estética Plástica (AECEP), La Sociedad Argentina de Cirugía Plástica, Estética y Reparadora (SACPER), the Rhinoplasty Society of Europe (RSE), the Iranian Society of Plastic and Aesthetic Surgeons (ISPAS), the Singapore Association of Plastic Surgeons (SAPS), the Australasian Society of Aesthetic Plastic Surgeons (ASAPS), the Egyptian Society of Plastic and Reconstructive Surgeons (ESPRS), and the Sociedad Chilena de Cirugía Plástica, Reconstructiva y Estética (SCCP).
Aesthetic Plastic Surgery provides a forum for original articles advancing the art of aesthetic plastic surgery. Many describe surgical craftsmanship; others deal with complications in surgical procedures and methods by which to treat or avoid them. Coverage includes "second thoughts" on established techniques, which might be abandoned, modified, or improved. Also included are case histories; improvements in surgical instruments, pharmaceuticals, and operating room equipment; and discussions of problems such as the role of psychosocial factors in the doctor-patient and the patient-public interrelationships.
Aesthetic Plastic Surgery is covered in Current Contents/Clinical Medicine, SciSearch, Research Alert, Index Medicus-Medline, and Excerpta Medica/Embase.