Cancer Symptom Clusters in Children and Adolescents with Cancer Undergoing Chemotherapy: A Systematic Review.

IF 2.4 Q1 NURSING

Nursing Reports Pub Date : 2025-05-07 DOI:10.3390/nursrep15050163

Luís Carlos Lopes-Júnior, Jonathan Grassi, Marcela Bortoleto Freitas, Fernanda Ercília Souza Trigo, Fabrine Aguilar Jardim, Karolini Zuqui Nunes, Karla Anacleto de Vasconcelos, Regina Aparecida Garcia de Lima

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引用次数: 0

Abstract

Objective: To synthesize and analyze the prevalence, composition, longitudinal stability, and predictors of cancer symptom clusters in children and adolescents undergoing chemotherapy. Method: A systematic literature review was conducted in accordance with the PRISMA 2020 guidelines. Evidence was sourced from MEDLINE/PubMed, Cochrane Library, Embase, PsycINFO, and Web of Science, as well as clinical trial registries (Clinical Trials WHO-ICTRP) and gray literature. The search was performed in February 2025, with no restrictions on publication date or language. Two independent reviewers screened and selected the studies. The methodological quality of the included studies was assessed using design-specific tools, and the findings were synthesized narratively. Results: A total of 6221 records were identified, with 12 studies meeting the inclusion criteria. These studies were published between 2010 and 2024 in the United States, Brazil, China, and Turkey. Cancer symptom clusters in children and adolescents followed well-defined patterns, with the gastrointestinal, emotional, fatigue-related, somatic, and self-image clusters being the most prevalent. Conclusions: Early identification of these cancer symptom clusters is essential for guiding interprofessional teams in delivering personalized, evidence-based care to children and adolescents with cancer and their families.

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接受化疗的儿童和青少年癌症症状群：系统综述。

目的：综合分析儿童和青少年化疗患者癌症症状群的患病率、组成、纵向稳定性及预测因素。方法：根据PRISMA 2020指南进行系统的文献综述。证据来自MEDLINE/PubMed、Cochrane图书馆、Embase、PsycINFO和Web of Science，以及临床试验注册（临床试验WHO-ICTRP）和灰色文献。搜索于2025年2月进行，没有发布日期和语言的限制。两名独立评审员对研究进行筛选和选择。使用特定设计工具评估纳入研究的方法学质量，并对研究结果进行叙述性综合。结果：共纳入6221篇文献，其中12篇符合纳入标准。这些研究于2010年至2024年间在美国、巴西、中国和土耳其发表。儿童和青少年的癌症症状集群遵循明确的模式，胃肠道、情绪、疲劳相关、躯体和自我形象集群是最普遍的。结论：早期识别这些癌症症状群对于指导跨专业团队为患有癌症的儿童和青少年及其家庭提供个性化的循证护理至关重要。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Nursing Reports NURSING-

CiteScore

2.50

自引率

4.20%

发文量

期刊介绍： Nursing Reports is an open access, peer-reviewed, online-only journal that aims to influence the art and science of nursing by making rigorously conducted research accessible and understood to the full spectrum of practicing nurses, academics, educators and interested members of the public. The journal represents an exhilarating opportunity to make a unique and significant contribution to nursing and the wider community by addressing topics, theories and issues that concern the whole field of Nursing Science, including research, practice, policy and education. The primary intent of the journal is to present scientifically sound and influential empirical and theoretical studies, critical reviews and open debates to the global community of nurses. Short reports, opinions and insight into the plight of nurses the world-over will provide a voice for those of all cultures, governments and perspectives. The emphasis of Nursing Reports will be on ensuring that the highest quality of evidence and contribution is made available to the greatest number of nurses. Nursing Reports aims to make original, evidence-based, peer-reviewed research available to the global community of nurses and to interested members of the public. In addition, reviews of the literature, open debates on professional issues and short reports from around the world are invited to contribute to our vibrant and dynamic journal. All published work will adhere to the most stringent ethical standards and journalistic principles of fairness, worth and credibility. Our journal publishes Editorials, Original Articles, Review articles, Critical Debates, Short Reports from Around the Globe and Letters to the Editor.