Assessment of pulmonary artery wall thickness by transthoracic echocardiography in Behçet's disease.

IF 1.9 4区医学 Q3 RHEUMATOLOGY

Modern Rheumatology Pub Date : 2025-09-02 DOI:10.1093/mr/roaf040

Gizem Kırmızıer, Elif Altunel Kılınç, Gizem Varkal, Zeynep Tüzün, İpek Türk, Rabia Eker Akıllı, Süleyman Özbek

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引用次数: 0

Abstract

Objectives: Vascular inflammation is a key feature of Behçet's disease (BD), with studies showing increased vein wall thickness. The pulmonary artery, sharing structural features with veins, is of particular importance in BD. This study aimed to assess pulmonary artery wall thickness (PAWT) using transthoracic echocardiography and examine its association with disease manifestations, including major organ involvement (MOI) and mucocutaneous-limited disease (MLD), in comparison to healthy controls (HCs).

Methods: This cross-sectional study included 67 patients with BD (43 with MOI, 24 with MLD) and 46 HCs. PAWT was measured from the middle of the pulmonary valve and pulmonary artery bifurcation in the parasternal short axis by an experienced cardiologist blinded to clinical data.

Results: PAWT was significantly higher in patients with BD (3.5 ± 0.9 mm) than in HCs (2.7 ± 0.5 mm) (P < .001). Patients with MOI had significantly greater thickness than those with MLD and HCs (3.9 ± 0.7, 2.7 ± 0.6, 2.7 ± 0.5 mm, respectively; P < .001). The increase in thickness was most pronounced in patients with vascular involvement (P = .03).

Conclusions: PAWT is greater in BD with MOI. Routine measurement may help detect vascular complications.

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经胸超声心动图评价behaperet病肺动脉壁厚度。

目的：血管炎症是behet病的一个关键特征，研究显示静脉壁厚度增加。肺动脉与静脉具有相同的结构特征，在behaperet病中尤为重要。本研究旨在通过经胸超声心动图评估肺动脉壁厚度，并检查其与疾病表现的关系，包括主要器官受累和粘膜皮肤局限性疾病，与健康对照进行比较。方法：本横断面研究包括67例behaperet病患者（43例主要器官受累，24例粘膜皮肤受限）和46例健康对照。肺动脉壁厚度由经验丰富的不了解临床数据的心脏病专家从肺动脉瓣的中间和胸骨旁短轴的肺动脉分叉处测量。结果：behet病患者肺动脉壁厚度（3.5±0.9 mm）明显高于健康对照组（2.7±0.5 mm） (p)。结论：累及主要脏器的behet病患者肺动脉壁厚度较大。常规测量有助于发现血管并发症。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Modern Rheumatology RHEUMATOLOGY-

CiteScore

4.90

自引率

9.10%

发文量

146

审稿时长

1.5 months

期刊介绍： Modern Rheumatology publishes original papers in English on research pertinent to rheumatology and associated areas such as pathology, physiology, clinical immunology, microbiology, biochemistry, experimental animal models, pharmacology, and orthopedic surgery. Occasional reviews of topics which may be of wide interest to the readership will be accepted. In addition, concise papers of special scientific importance that represent definitive and original studies will be considered. Modern Rheumatology is currently indexed in Science Citation Index Expanded (SciSearch), Journal Citation Reports/Science Edition, PubMed/Medline, SCOPUS, EMBASE, Chemical Abstracts Service (CAS), Google Scholar, EBSCO, CSA, Academic OneFile, Current Abstracts, Elsevier Biobase, Gale, Health Reference Center Academic, OCLC, SCImago, Summon by Serial Solutions