A Comprehensive Literature Review of Total Hip Arthroplasty (THA): Part 1-Biomaterials.

IF 5 3区医学 Q1 ENGINEERING, BIOMEDICAL

Journal of Functional Biomaterials Pub Date : 2025-05-14 DOI:10.3390/jfb16050179

Chiara Morano, Salvatore Garofalo, Paolo Bertuccio, Agata Sposato, Irene Zappone, Leonardo Pagnotta

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Abstract

The rapid advancement of materials science has revolutionized total hip arthroplasty (THA), a critical orthopedic procedure aimed at restoring mobility and improving patient quality of life. This review investigates the evolution of biomaterials used in THA, analyzing their mechanical, biological, and chemical properties. The study outlines the transition from early natural materials to modern metals, polymers, and ceramics, highlighting their benefits and limitations in clinical applications. Particular emphasis is placed on the development of advanced materials such as highly cross-linked polyethylene (HXLPE), zirconia-toughened alumina (ZTA), and tantalum alloys (Ta), which demonstrate enhanced biocompatibility, wear resistance, and longevity. By examining emerging trends, including bioactive coatings and nanotechnology, this paper aims to provide a comprehensive understanding of current challenges and future directions in material selection for hip prostheses, ultimately aiming to minimize annual revision rates and improve long-term outcomes.

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全髋关节置换术的综合文献综述：第1部分-生物材料。

材料科学的快速发展已经彻底改变了全髋关节置换术（THA），这是一项关键的骨科手术，旨在恢复活动能力和提高患者的生活质量。本文综述了用于THA的生物材料的发展，分析了它们的力学、生物学和化学性质。该研究概述了从早期天然材料到现代金属、聚合物和陶瓷的转变，强调了它们在临床应用中的优点和局限性。特别强调的是先进材料的开发，如高交联聚乙烯（HXLPE），氧化锆增韧氧化铝（ZTA）和钽合金（Ta），这些材料表现出增强的生物相容性，耐磨性和寿命。通过研究包括生物活性涂层和纳米技术在内的新兴趋势，本文旨在全面了解髋关节假体材料选择的当前挑战和未来方向，最终旨在最大限度地减少年度翻修率并改善长期效果。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Journal of Functional Biomaterials Engineering-Biomedical Engineering

CiteScore

4.60

自引率

4.20%

发文量

226

审稿时长

11 weeks

期刊介绍： Journal of Functional Biomaterials (JFB, ISSN 2079-4983) is an international and interdisciplinary scientific journal that publishes regular research papers (articles), reviews and short communications about applications of materials for biomedical use. JFB covers subjects from chemistry, pharmacy, biology, physics over to engineering. The journal focuses on the preparation, performance and use of functional biomaterials in biomedical devices and their behaviour in physiological environments. Our aim is to encourage scientists to publish their results in as much detail as possible. Therefore, there is no restriction on the length of the papers. The full experimental details must be provided so that the results can be reproduced. Several topical special issues will be published. Scope: adhesion, adsorption, biocompatibility, biohybrid materials, bio-inert materials, biomaterials, biomedical devices, biomimetic materials, bone repair, cardiovascular devices, ceramics, composite materials, dental implants, dental materials, drug delivery systems, functional biopolymers, glasses, hyper branched polymers, molecularly imprinted polymers (MIPs), nanomedicine, nanoparticles, nanotechnology, natural materials, self-assembly smart materials, stimuli responsive materials, surface modification, tissue devices, tissue engineering, tissue-derived materials, urological devices.