Letter to the editor: heterogeneity in effects of PDA treatment.

IF 3 3区医学 Q1 PEDIATRICS

European Journal of Pediatrics Pub Date : 2025-05-27 DOI:10.1007/s00431-025-06192-8

William E Benitz

引用次数: 0

Abstract

The recent meta-analysis by Matsushita et al on "Heterogeneity in treatment response for patent ductus arteriosus" confirms prior results showing that medical treatment of PDA does not reduce but increases mortality. The discussion implies that there is heterogeneity in effects of treatment on mortality, but this is not consistent with the data. The implication of their analysis is that early medical treatment of PDA in preterm infants should be abandoned, as recommended in the recent Clinical Report from the American Academy of Pediatrics.

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致编辑的信：PDA治疗效果的异质性。

最近Matsushita等人关于“动脉导管未闭治疗反应的异质性”的荟萃分析证实了先前的结果，即PDA的药物治疗不会降低而是会增加死亡率。讨论表明，治疗对死亡率的影响存在异质性，但这与数据不一致。他们的分析暗示，正如美国儿科学会最近的临床报告所建议的那样，应该放弃对早产儿PDA的早期医学治疗。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

European Journal of Pediatrics 医学-小儿科

CiteScore

5.90

自引率

2.80%

发文量

367

审稿时长

3-6 weeks

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