Upcycling glycerol into succinic acid: sustainable integration with biodiesel mills.

Abstract

This study explores the industrial potential of producing bio-based succinic acid (SA) from crude glycerol, a low-value byproduct of Brazil's biodiesel industry. By integrating green chemistry and biotechnology, the research aims to upcycle crude glycerol into high-value SA. Using Yarrowia lipolytica as a natural SA producer, the study assesses standalone facilities and systems integrated into biodiesel mills. Results show that producing SA from crude glycerol (S1) reduces climate change impact by 47% compared to using pure glycerol (S2), despite lower productivity. Integrating SA production with biodiesel operations (S3) improves economic performance but raises CO₂ emissions by 54% relative to standalone biodiesel production (S1). All scenarios are economically feasible, with payback periods under seven years. Energy use and solvent recovery optimization remain essential to boost competitiveness. This work underscores the potential to upcycle crude glycerol, supporting circular economy strategies and informing sustainable biorefinery development and policy.