3D Microtumors Representing Ovarian Cancer Minimal Residual Disease Respond to the Fatty Acid Oxidation Inhibitor Perhexiline (Adv. Healthcare Mater. 14/2025)

IF 10 2区医学 Q1 ENGINEERING, BIOMEDICAL

Advanced Healthcare Materials Pub Date : 2025-05-28 DOI:10.1002/adhm.202570082

Xingyun Yang, Mara Artibani, Yongcheng Jin, Aneesh Aggarwal, Yujia Zhang, Sandra Muñoz-Galvan, Ellina Mikhailova, Lena Rai, Nobina Mukherjee, Ravinash Krishna Kumar, Ashwag Albukhari, Shaohua Ma, Linna Zhou, Ahmed Ashour Ahmed, Hagan Bayley

引用次数: 0

Abstract

Minimal Residual Disease

The cover image depicts 3D microtumors created with a microfluidic system. The microtumors retain key features of ovarian cancer minimal residual disease (MRD), a major cause of cancer recurrence. The in vitro model serves as a platform for testing therapeutics, and can support personalized treatment. More details can be found in article 2404072 by Linna Zhou, Ahmed Ashour Ahmed, Hagan Bayley, and co-workers.

查看原文本刊更多论文

代表卵巢癌微小残留病的3D微肿瘤对脂肪酸氧化抑制剂过己胺的反应（Adv. Healthcare Mater. 14/2025）

最小残留疾病封面图像描绘了用微流体系统创建的3D微肿瘤。微肿瘤保留了卵巢癌微小残留病（MRD）的主要特征，这是癌症复发的主要原因。体外模型作为测试治疗方法的平台，可以支持个性化治疗。更多细节可以在Linna Zhou， Ahmed Ashour Ahmed， Hagan Bayley及其同事的文章2404072中找到。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Advanced Healthcare Materials 工程技术-生物材料

CiteScore

14.40

自引率

3.00%

发文量

600

审稿时长

1.8 months

期刊介绍： Advanced Healthcare Materials, a distinguished member of the esteemed Advanced portfolio, has been dedicated to disseminating cutting-edge research on materials, devices, and technologies for enhancing human well-being for over ten years. As a comprehensive journal, it encompasses a wide range of disciplines such as biomaterials, biointerfaces, nanomedicine and nanotechnology, tissue engineering, and regenerative medicine.