Enhanced electrochemical activity by MOF superstructure derived Ni2P@C for ultrasensitive sensing of Bisphenol A

IF 10.7 1区生物学 Q1 BIOPHYSICS

Biosensors and Bioelectronics Pub Date : 2025-05-19 DOI:10.1016/j.bios.2025.117598

Pan Gao , Mian Zahid Hussain , David Gryc , Soumya Mukherjee , Zhenyu Zhou , Weijin Li , Andreas Jentys , Martin Elsner , Roland A. Fischer

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引用次数: 0

Abstract

Electrochemical (EC) sensing of bisphenol A (BPA), a notorious persistent contaminant, is of pressing interest. However, the state-of-the-art BPA sensors are challenged by two performance parameters: limited EC catalysis and sensitivity. Herein, a two-dimensional (2D) metal-organic framework (MOF) superstructure-derived Ni₂P@C probe elicits a novel EC sensor that exhibits high-efficiency BPA detection. Thanks to the abundant Ni^δ+ active sites exposed uniformly on cross-linked layers stemming from the inherited 2D-MOF superstructures as the precursors, high conductivity results from the organic linkers-derived graphitic carbon. The prepared Ni₂P@C composites-based EC sensors demonstrated exceptional BPA-induced sensing responses with a wide dynamic response range, high sensitivity of 0.951 μA cm⁻²·μM⁻¹, a low limit of detection (LOD, 56.8 nM) in the linear range of 1 μM–100 μM. Below 1 μM, the response followed the logarithm of BPA concentrations, indicating the potential for detection down to 5 pM. The excellent selectivity in the presence of similar interferents, combined with high reproducibility and chemical stability, underscores the potential of 2D MOF-derived Ni₂P@C for accurate monitoring of hazardous phenols, opening new avenues for environmental sensing and remediation.

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MOF超结构Ni2P@C对双酚A超灵敏传感增强电化学活性

双酚A （BPA）是一种臭名昭著的持久性污染物，它的电化学（EC）传感是一个紧迫的问题。然而，最先进的双酚a传感器受到两个性能参数的挑战：有限的EC催化和灵敏度。本文中，二维（2D）金属有机框架（MOF）上层结构衍生Ni2P@C探针引出了一种新型EC传感器，该传感器能够高效检测BPA。由于继承了2D-MOF超结构作为前驱体，在交联层上均匀暴露了丰富的ni +活性位点，因此有机连接剂衍生的石墨碳具有高导电性。所制备的Ni2P@C复合材料的EC传感器具有良好的动态响应范围，灵敏度为0.951 μA cm−2·μM−1，在1 μM - 100 μM的线性范围内具有较低的检出限（LOD, 56.8 nM）。在1 μM以下，响应服从BPA浓度的对数，表明可以检测到5pm。在类似干扰存在下的优异选择性，加上高重现性和化学稳定性，强调了2D mof衍生的Ni2P@C在精确监测有害酚类方面的潜力，为环境传感和修复开辟了新的途径。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Biosensors and Bioelectronics 工程技术-电化学

CiteScore

20.80

自引率

7.10%

发文量

1006

审稿时长

29 days

期刊介绍： Biosensors & Bioelectronics, along with its open access companion journal Biosensors & Bioelectronics: X, is the leading international publication in the field of biosensors and bioelectronics. It covers research, design, development, and application of biosensors, which are analytical devices incorporating biological materials with physicochemical transducers. These devices, including sensors, DNA chips, electronic noses, and lab-on-a-chip, produce digital signals proportional to specific analytes. Examples include immunosensors and enzyme-based biosensors, applied in various fields such as medicine, environmental monitoring, and food industry. The journal also focuses on molecular and supramolecular structures for enhancing device performance.