Viral agents in neuromuscular pathology.

International review of neurobiology Pub Date : 2025-01-01 Epub Date: 2025-05-05 DOI:10.1016/bs.irn.2025.04.007
Abhay Kumar Singh, Yemgadda Goutham Sudhan, Ramakrisha Ramakrishna, Siva Sundara Kumar Durairajan
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引用次数: 0

Abstract

In recent years, viral infections have been increasingly identified as major players in neuromuscular pathologies. This chapter presents an overview of the evidence and future directions for virus-induced neuromuscular disorders. Information is integrated on the global burden of these diseases related to epidemiology, clinical features, diagnosis, treatment, and preventive strategies was integrated. Responsible viruses include enteroviruses, flaviviruses, herpesviruses, and emerging pathogens such as SARS-CoV-2. It represents a broad spectrum of neuromuscular disorders, including Guillain-Barré syndrome, viral myositis, and critical illness neuropathy/myopathy. The book chapter discusses different diagnostic approaches, therapy strategies, and rehabilitation methods, in addition to early intervention and preventive measures. This has led to new insights into novel therapies, unmet research needs, and future perspectives on viral neuromuscular disorders. This chapter demonstrates that supporting both clinical care and patient management with clinical research entails a profound understanding of the difficult interactions between the viruses concerned and the neuromuscular system.

神经肌肉病理学中的病毒因子。
近年来,病毒感染已越来越多地被确定为神经肌肉病变的主要参与者。本章概述了病毒引起的神经肌肉疾病的证据和未来发展方向。关于这些疾病的全球负担的信息被整合,包括流行病学、临床特征、诊断、治疗和预防战略。负责任的病毒包括肠病毒、黄病毒、疱疹病毒和新出现的病原体,如SARS-CoV-2。它代表了广泛的神经肌肉疾病,包括格林-巴利综合征、病毒性肌炎和重症神经病/肌病。该书章节讨论了不同的诊断方法、治疗策略和康复方法,以及早期干预和预防措施。这导致了对新疗法的新见解,未满足的研究需求,以及对病毒性神经肌肉疾病的未来展望。本章表明,通过临床研究支持临床护理和患者管理需要对有关病毒与神经肌肉系统之间的困难相互作用有深刻的理解。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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