Wen Chen, Lan Yang, Xinyu Zhang, Le Ren, Chucan Wang, Jiayi Wang, Xinyao Zheng, Jinfang Wu
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引用次数: 0
Abstract
Background: This study evaluates the effects of a modest reduction in back optic zone diameter (BOZD) in orthokeratology (ortho-k) lenses on axial elongation and visual performance. The goal is to determine whether this adjustment enhances myopia control in children with rapid progression and suboptimal outcomes, while maintaining visual quality and exploring the underlying mechanisms.
Methods: This retrospective study analyzed data from 109 myopic children undergoing ortho-k fitting over two years. The continued group wore traditional 6.0 mm BOZD lenses, while the switched group wore 6.0 mm lenses in the first year and transitioned to 5.8 mm BOZD lenses in the second year. The changes of Axial length (AL) elongation and corneal topography parameters, including treatment zone (TZ) size, cumulative relative corneal refractive power within a 4.80 mm diameter (Sum4.8), TZ decentration, and percentage of defocus zone within the pupil area (PDZP).
Results: In the continued and switched groups, the baseline age was 9.92 ± 2.19 and 9.38 ± 1.58 years, respectively. During the second year, the switched group exhibited a significantly reduced AL elongation compared to the continued group (0.17 ± 0.24 mm vs 0.28 ± 0.17 mm, p = 0.02). Additionally, Sum4.8 was significantly elevated in the continued group. However, there wasno significant differences in TZ size and decentration, or PDZP between the two groups, indicating that the 0.2 mm reduction in BOZD may not be sufficient to influence these parameters.
Conclusions: The transition to a BOZD of 5.8 mm improved myopia management by mitigating AL elongation without producing visual problems, possibly attributable to an augmented peripheral myopic defocus. This study offers empirical support for the clinical advantages of decreasing BOZD in ortho-k for pediatric patients with suboptimal myopia control.
背景:本研究评估适度减少角膜塑形(orthokeratology)镜片后视区直径(BOZD)对轴向延伸和视觉表现的影响。目的是确定这种调整是否能在保持视觉质量和探索潜在机制的同时,增强快速进展和次优结局儿童的近视控制。方法:回顾性分析两年来109例近视儿童的orthok配合术资料。继续组佩戴传统的6.0 mm BOZD镜片,切换组第一年佩戴6.0 mm镜片,第二年过渡到5.8 mm BOZD镜片。轴长(AL)伸长率和角膜地形参数的变化,包括治疗区(TZ)大小、4.80 mm直径范围内角膜累计相对屈光度(Sum4.8)、TZ分散度和瞳孔区域内离焦区百分比(PDZP)。结果:继续组和切换组的基线年龄分别为9.92±2.19岁和9.38±1.58岁。在第二年,与继续组相比,切换组的AL伸长明显减少(0.17±0.24 mm vs 0.28±0.17 mm, p = 0.02)。此外,持续用药组的Sum4.8显著升高。然而,两组之间TZ大小和分散性或PDZP没有显著差异,表明BOZD减少0.2 mm可能不足以影响这些参数。结论:过渡到5.8 mm的BOZD通过减轻AL伸长而改善了近视管理,而不会产生视力问题,这可能是由于周围性近视离焦的增强。本研究为降低儿童近视控制不佳患者在ortho-k中BOZD的临床优势提供了实证支持。
期刊介绍:
Contact Lens & Anterior Eye is a research-based journal covering all aspects of contact lens theory and practice, including original articles on invention and innovations, as well as the regular features of: Case Reports; Literary Reviews; Editorials; Instrumentation and Techniques and Dates of Professional Meetings.