Assessing the impact of nicotine and non-tobacco nicotine use on postoperative complications following hallux valgus surgery.

IF 1.9 3区医学 Q2 ORTHOPEDICS

Foot and Ankle Surgery Pub Date : 2025-05-20 DOI:10.1016/j.fas.2025.05.008

Apurvakumar Patel, Joshua Wang, Teerth Y Patel, Megna Panchbhavi, Vinod K Panchbhavi

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引用次数: 0

Abstract

Background: Nicotine use, including from non-tobacco sources, is associated with impaired wound healing and increased surgical complications. This study evaluated the impact of nicotine and non-tobacco nicotine use on postoperative outcomes in hallux valgus (HV) surgeries.

Methods: Using the TriNetX Global Health Research Network, we analyzed adult patients aged 18 and older undergoing HV correction. Cohorts included nicotine users, non-tobacco nicotine users, and controls, matched using propensity score matching (PSM). Postoperative complications were assessed within 90 days.

Results: Both nicotine and non-tobacco nicotine cohorts demonstrated increased postoperative complications compared to the control cohort, notably infections, wound disruption, stroke, pneumonia, and renal failure. Also, both nicotine and non-tobacco nicotine users showed elevated healthcare utilization, including emergency department visits and opioid-related disorders.

Conclusions: Nicotine and non-tobacco nicotine use significantly increase the risk of postoperative complications following HV surgery, emphasizing the importance of mitigating these risks through further research and preoperative strategies.

Level of evidence: Level III, Retrospective Comparative Study.

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评估尼古丁和非烟草尼古丁使用对拇外翻手术后并发症的影响。

背景：尼古丁使用，包括非烟草来源，与伤口愈合受损和手术并发症增加有关。本研究评估了尼古丁和非烟草尼古丁使用对拇外翻（HV）手术后预后的影响。方法：使用TriNetX全球健康研究网络，我们分析了18岁及以上接受HV矫正的成年患者。队列包括尼古丁使用者、非烟草尼古丁使用者和对照组，使用倾向评分匹配（PSM）进行匹配。术后90天内评估并发症。结果：与对照组相比，尼古丁组和非烟草尼古丁组均表现出术后并发症增加，特别是感染、伤口破裂、中风、肺炎和肾衰竭。此外，尼古丁和非烟草尼古丁使用者都显示出更高的医疗保健利用率，包括急诊就诊和阿片类药物相关疾病。结论：尼古丁和非烟草尼古丁使用显著增加HV手术后并发症的风险，强调通过进一步研究和术前策略降低这些风险的重要性。证据等级：III级，回顾性比较研究。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Foot and Ankle Surgery ORTHOPEDICS-

CiteScore

4.60

自引率

16.00%

发文量

202

期刊介绍： Foot and Ankle Surgery is essential reading for everyone interested in the foot and ankle and its disorders. The approach is broad and includes all aspects of the subject from basic science to clinical management. Problems of both children and adults are included, as is trauma and chronic disease. Foot and Ankle Surgery is the official journal of European Foot and Ankle Society. The aims of this journal are to promote the art and science of ankle and foot surgery, to publish peer-reviewed research articles, to provide regular reviews by acknowledged experts on common problems, and to provide a forum for discussion with letters to the Editors. Reviews of books are also published. Papers are invited for possible publication in Foot and Ankle Surgery on the understanding that the material has not been published elsewhere or accepted for publication in another journal and does not infringe prior copyright.