Corentin J Gosling, Ariane Cartigny, Linda Scoriels, Céline Portalier, Charles Laidi, Jasmina Mallet
{"title":"[Cognitive flexibility: a key cognitive dimension].","authors":"Corentin J Gosling, Ariane Cartigny, Linda Scoriels, Céline Portalier, Charles Laidi, Jasmina Mallet","doi":"10.1051/medsci/2025075","DOIUrl":null,"url":null,"abstract":"<p><p>Cognitive flexibility, an essential executive function, allows adaptation to environmental changes and represents a fundamental pillar of executive function in neuropsychological models. Based on neurobiological advances and clinical observations, it has emerged as a promising transdiagnostic marker for several psychiatric pathologies, including mood disorders, schizophrenia, and autism spectrum disorders. This review examines the specific role of cognitive flexibility among other cognitive functions, explores potential therapeutic approaches, and presents its evaluation in human and animal models as part of PEPR PROPSY. As the chapters unfold, readers will deepen their understanding of cognitive flexibility while discovering promising avenues for both assessment methods and intervention strategies.</p>","PeriodicalId":18205,"journal":{"name":"M S-medecine Sciences","volume":"41 5","pages":"443-450"},"PeriodicalIF":0.4000,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"M S-medecine Sciences","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1051/medsci/2025075","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2025/5/26 0:00:00","PubModel":"Epub","JCR":"Q4","JCRName":"MEDICINE, RESEARCH & EXPERIMENTAL","Score":null,"Total":0}
引用次数: 0
Abstract
Cognitive flexibility, an essential executive function, allows adaptation to environmental changes and represents a fundamental pillar of executive function in neuropsychological models. Based on neurobiological advances and clinical observations, it has emerged as a promising transdiagnostic marker for several psychiatric pathologies, including mood disorders, schizophrenia, and autism spectrum disorders. This review examines the specific role of cognitive flexibility among other cognitive functions, explores potential therapeutic approaches, and presents its evaluation in human and animal models as part of PEPR PROPSY. As the chapters unfold, readers will deepen their understanding of cognitive flexibility while discovering promising avenues for both assessment methods and intervention strategies.
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m/s offers high-quality review articles in French, covering all areas of biomedical and health research, in a monthly magazine format (10 issues / year). m/s is read by the whole French-speaking community, in France but also in Belgium, Switzerland, Canada, Morocco, Algeria, Tunisia etc. m/s is not a primary publication, and thus will not consider unpublished data. Most articles are invited by the Editors, but spontaneous proposals are welcomed. Each issue combines news and views on the most recent scientific publications, as well as broadly accessible and updated review articles on a specific topic, and essays on science and society, history of science, public health, or reactions to published articles. Each year, m/s also publishes one or two thematic issues focused on a research topic of high interest. All review articles and essays are peer-reviewed.
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