[Brain imaging and the first success of precision psychiatry].

IF 0.4 4区 医学 Q4 MEDICINE, RESEARCH & EXPERIMENTAL
M S-medecine Sciences Pub Date : 2025-05-01 Epub Date: 2025-05-26 DOI:10.1051/medsci/2025061
Charles Laidi, Noomane Bouaziz, Emmanuel Haffen, Philippe Domenech, Edouard Duchesnay, Pauline Favre, Éric Fakra, Josselin Houenou, Anton Iftimovici, Antoine Lefrere, Mircea Polosan, Guillaume Sescousse, Anne Sauvaget, Renaud Jardri
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引用次数: 0

Abstract

Magnetic resonance imaging (MRI) can be used to investigate the neurobiological basis of psychiatric disorders such as schizophrenia, bipolar disorders, autism spectrum disorders and resistant depression. Although differences in cortical thickness between patients and controls have been well demonstrated, there is currently no valid MRI-based biomarker for psychiatric disorders. The challenge of precision psychiatry is to develop biomarkers, that are specific for a given pathology or clinical dimension, but also capable of predicting clinical evolution or response to treatment, to transform patient management. Functional magnetic resonance imaging could also be a promising tool for the individualized targeting of non-invasive neuromodulation in depression or resistant hallucinations, as well as for functional magnetic resonance imaging-based neurofeedback.

[脑成像和精确精神病学的首次成功]。
磁共振成像(MRI)可用于研究精神疾病的神经生物学基础,如精神分裂症、双相情感障碍、自闭症谱系障碍和难治性抑郁症。尽管已经很好地证明了患者和对照组之间皮层厚度的差异,但目前还没有有效的基于mri的精神疾病生物标志物。精确精神病学面临的挑战是开发生物标志物,既针对特定的病理或临床维度,又能够预测临床发展或对治疗的反应,从而改变患者管理。功能性磁共振成像也可能是一种有前途的工具,用于针对抑郁症或抗性幻觉的非侵入性神经调节的个体化靶向,以及基于功能性磁共振成像的神经反馈。
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来源期刊
M S-medecine Sciences
M S-medecine Sciences 医学-医学:研究与实验
CiteScore
0.80
自引率
14.30%
发文量
182
审稿时长
4-8 weeks
期刊介绍: m/s offers high-quality review articles in French, covering all areas of biomedical and health research, in a monthly magazine format (10 issues / year). m/s is read by the whole French-speaking community, in France but also in Belgium, Switzerland, Canada, Morocco, Algeria, Tunisia etc. m/s is not a primary publication, and thus will not consider unpublished data. Most articles are invited by the Editors, but spontaneous proposals are welcomed. Each issue combines news and views on the most recent scientific publications, as well as broadly accessible and updated review articles on a specific topic, and essays on science and society, history of science, public health, or reactions to published articles. Each year, m/s also publishes one or two thematic issues focused on a research topic of high interest. All review articles and essays are peer-reviewed.
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