Cardiovascular risk and lipid control in older adults: Compliance with LDL, non-HDL cholesterol, and triglyceride goals in a national cross-sectional study.

IF 3.6 3区医学 Q2 PHARMACOLOGY & PHARMACY

Journal of clinical lipidology Pub Date : 2025-05-07 DOI:10.1016/j.jacl.2025.04.197

Cristian Orlando Porras Bueno, Jesús Andres Beltrán España, Carolina Murgueitio Guzmán, Cándida Diaz-Brochero, Ángel Alberto García Peña

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引用次数: 0

Abstract

Background: Cardiovascular diseases (CVDs) are the leading cause of mortality worldwide. Low-density lipoprotein cholesterol (LDL-C) is a key therapeutic target, yet data on compliance with lipid goals in older adults from low- and middle-income countries are limited.

Objective: To evaluate the compliance with lipid profile goals in older adults.

Methods: This cross-sectional study analyzed 1270 adults aged ≥60 years from the Survey on Health, Well-being, and Ageing in Latin America and the Caribbean (SABE) Colombia 2015 survey. Cardiovascular risk was assessed via Framingham, ASCVD 2013, and SCORE2 models calibrated for Colombia, and lipid profile compliance was evaluated.

Results: Most participants were at high or very high risk according to the SCORE2 (54.10%), ASCVD (10%), and Framingham (10.87%) criteria. LDL-C target compliance was low, ranging from 0.72% (Framingham) to 3.93% (ASCVD). Triglyceride targets were better achieved, with 54.88% meeting goals in the highest SCORE2 category.

Conclusions: Older Colombian adults have poor compliance with lipid goals, underscoring the urgent need for enhanced preventive strategies in this population.

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老年人心血管风险和脂质控制：一项全国性横断面研究中LDL、非hdl胆固醇和甘油三酯目标的依从性

背景：心血管疾病（cvd）是世界范围内导致死亡的主要原因。低密度脂蛋白胆固醇（LDL-C）是一个关键的治疗靶点，然而关于中低收入国家老年人脂质目标依从性的数据有限。目的：评价老年人血脂指标的依从性。方法：本横断面研究分析了拉丁美洲和加勒比地区健康、福祉和老龄化调查（SABE）哥伦比亚2015年调查中1270名年龄≥60岁的成年人。通过Framingham、ASCVD 2013和哥伦比亚校准的SCORE2模型评估心血管风险，并评估血脂依从性。结果：根据SCORE2（54.10%）、ASCVD（10%）和Framingham（10.87%）标准，大多数参与者处于高风险或极高风险。LDL-C目标依从性较低，范围从0.72% （Framingham）到3.93% （ASCVD）。甘油三酯指标较好地实现，54.88%达到最高SCORE2类别的目标。结论：哥伦比亚老年人对血脂目标的依从性较差，强调迫切需要在这一人群中加强预防策略。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Journal of clinical lipidology 医学-药学

CiteScore

7.00

自引率

6.80%

发文量

209

审稿时长

49 days

期刊介绍： Because the scope of clinical lipidology is broad, the topics addressed by the Journal are equally diverse. Typical articles explore lipidology as it is practiced in the treatment setting, recent developments in pharmacological research, reports of treatment and trials, case studies, the impact of lifestyle modification, and similar academic material of interest to the practitioner. Sections of Journal of clinical lipidology will address pioneering studies and the clinicians who conduct them, case studies, ethical standards and conduct, professional guidance such as ATP and NCEP, editorial commentary, letters from readers, National Lipid Association (NLA) news and upcoming event information, as well as abstracts from the NLA annual scientific sessions and the scientific forums held by its chapters, when appropriate.