Biological disturbance of MiR-425 and its application prospects in cardiovascular diseases.

IF 4.6 2区生物学 Q2 CELL BIOLOGY

Frontiers in Cell and Developmental Biology Pub Date : 2025-05-09 eCollection Date: 2025-01-01 DOI:10.3389/fcell.2025.1593241

Shan Zhou, Bo Han

引用次数: 0

Abstract

MiR-425 is a biological molecule that has potential applications in cardiovascular diseases. It can regulate biological functions by combining with LncRNAs, binding with proteins, and changing the differentiation of immune cells. MiR-425 also has a role as a biomarker of disease. In cardiovascular diseases, it has clinical significance in reducing inflammation and heart repair, inducing angiogenesis, improving the prediction of atherosclerosis, reducing cardiac fibrosis, and regulating atrial natriuretic peptide to affect cardiovascular function. Target gene prediction and KEGG enrichment analysis are also mentioned.

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MiR-425的生物干扰及其在心血管疾病中的应用前景

MiR-425是一种生物分子，在心血管疾病中有潜在的应用。通过与LncRNAs结合，与蛋白质结合，改变免疫细胞的分化，调节生物功能。MiR-425还具有疾病生物标志物的作用。在心血管疾病中，在减少炎症和心脏修复、诱导血管生成、改善动脉粥样硬化预测、减少心脏纤维化、调节心房利钠肽影响心血管功能等方面具有临床意义。靶基因预测和KEGG富集分析也被提及。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Frontiers in Cell and Developmental Biology Biochemistry, Genetics and Molecular Biology-Cell Biology

CiteScore

9.70

自引率

3.60%

发文量

2531

审稿时长

12 weeks

期刊介绍： Frontiers in Cell and Developmental Biology is a broad-scope, interdisciplinary open-access journal, focusing on the fundamental processes of life, led by Prof Amanda Fisher and supported by a geographically diverse, high-quality editorial board. The journal welcomes submissions on a wide spectrum of cell and developmental biology, covering intracellular and extracellular dynamics, with sections focusing on signaling, adhesion, migration, cell death and survival and membrane trafficking. Additionally, the journal offers sections dedicated to the cutting edge of fundamental and translational research in molecular medicine and stem cell biology. With a collaborative, rigorous and transparent peer-review, the journal produces the highest scientific quality in both fundamental and applied research, and advanced article level metrics measure the real-time impact and influence of each publication.